Can I take Amlodipine and Metformin together?
Drug interaction guide
Originally published 25 Jan 2026
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Amlodipine may slightly reduce the blood sugar-lowering effects of metformin. This means your blood sugar levels might be a little higher than usual when taking both medicines together.
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Why this happens
Amlodipine belongs to a class of drugs called calcium channel blockers. These can sometimes interfere with how the body releases insulin and how it processes sugar, which can slightly oppose the work that metformin does to lower blood sugar.
What you should do
It is generally safe to take these two medicines together, as the interaction is mild. However, you should monitor your blood sugar levels more closely when you first start amlodipine or if your dose is increased. If you notice your blood sugar readings are consistently higher than your target range, speak to your doctor, as they may need to adjust your metformin dose.
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Using other medicines
Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Descargo de responsabilidad
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Historia del artículo
La información de esta página ha sido redactada y revisada por médicos cualificados.
25 Enero 2026 | Publicado originalmente

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