Can I take Amitriptyline and Paracetamol together?

It is generally considered safe to take amitriptilina y paracetamol together.

Amitriptyline and paracetamol are processed by the body using different pathways and do not interfere with how the other drug works, is absorbed, or is cleared from the system.

How to take amitriptyline and paracetamol

• You can take these medicines together as prescribed or according to the packet instructions.

• Always ensure you do not exceed the maximum daily dose of paracetamol (usually 4 grams or eight 500mg tablets in 24 hours).

• If you feel unusually drowsy, speak to your doctor or pharmacist.

Pensamientos suicidas y cambios de humor

La amitriptilina puede aumentar el riesgo de pensamientos suicidas o autolesiones, especialmente al comenzar el tratamiento o al cambiar las dosis. Busque ayuda médica inmediata si su estado de ánimo cambia o se siente deprimido.

Liver disease or heavy alcohol consumption

Taking paracetamol if you have liver problems or drink large amounts of alcohol significantly increases the risk of severe, life-threatening liver damage, even at standard doses.

Heart conditions (e.g. recent heart attack, heart rhythm disorders)

Amitriptyline can affect your heart rhythm and should not be used if you have recently had a heart attack or have certain heart rhythm problems, as it may lead to dangerous cardiac events.

Glaucoma (specifically acute angle-closure glaucoma)

Amitriptyline can increase the pressure inside your eye. If you have glaucoma, it can trigger an acute attack, which is a medical emergency.

Alcohol

Beber alcohol mientras tomas amitriptilina puede hacerte sentir muy somnoliento e inestable al caminar. Es mejor evitar el alcohol, especialmente cuando comienzas el tratamiento o si tu dosis se incrementa.

Cafeína (café, té, bebidas energéticas)

Amitriptyline can sometimes cause a fast or irregular heartbeat. High amounts of caffeine can worsen these side effects or increase feelings of anxiety and restlessness.

Taking multiple medicines? Our Verificador de Interacciones de Medicamentos helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Descargo de responsabilidad

Esta información es solo para fines educativos generales y no debe considerarse como un sustituto del consejo médico profesional. Siempre consulte a su médico de cabecera, farmacéutico u otro profesional de la salud calificado antes de tomar decisiones sobre sus medicamentos. Las circunstancias individuales pueden variar, y solo un profesional de la salud que conozca su historial médico puede proporcionar orientación personalizada.