Can I take Metformin and Ibuprofen together?

Por qué sucede esto

Ibuprofen can reduce blood flow to the kidneys and affect how well they filter waste. Since metformin is removed from the body by the kidneys, any decrease in kidney function can cause metformin levels to build up. High levels of metformin increase the risk of lactic acidosis (a dangerous build-up of acid in the blood).

Use with caution. If you need pain relief, paracetamol is generally a safer choice for people taking metformin. If you must take ibuprofen, keep the dose low and only use it for a short time. Stay well-hydrated and speak to your doctor if you feel unusually tired, dizzy, or have stomach pain, as these can be early signs of lactic acidosis.

Lactic acidosis risk (Dehydration)

If you develop severe vomiting, diarrhoea, or a high fever, stop taking metformin and contact a doctor immediately. These conditions can lead to severe dehydration, which significantly increases the risk of a rare but life-threatening build-up of acid in the blood (lactic acidosis).

Asma

No tome ibuprofeno si tiene asma, ya que puede causar un empeoramiento potencialmente mortal de su respiración o una reacción alérgica grave.

Enfermedad grave de riñón o hígado

You must stop taking metformin if you become severely dehydrated or develop a serious infection, as this can lead to a dangerous build-up of acid in the blood (lactic acidosis).

Stomach ulcers or kidney problems

Avoid ibuprofen if you have a history of stomach ulcers or kidney disease, as it can cause internal bleeding or sudden kidney failure.

Embarazo (tercer trimestre)

No tome ibuprofeno si tiene más de 6 meses de embarazo, ya que puede causar problemas graves de corazón y riñón en el bebé no nacido y complicaciones durante el parto.

Contrast dye scans (e.g., CT or X-ray)

You must tell your doctor you take metformin if you are having a scan involving an injection of 'contrast dye'. You will usually need to stop taking metformin 48 hours before and after the procedure to prevent kidney damage.

Alcohol

Drinking alcohol while taking metformin can increase the risk of a rare but serious condition called lactic acidosis. It can also affect your blood sugar control and increase the risk of low blood sugar (hypoglycaemia). It is best to avoid excessive drinking and binge drinking.

It is best to avoid or strictly limit alcohol while taking ibuprofen. Combining alcohol with non-steroidal anti-inflammatory drugs (NSAIDs) like ibuprofen increases the risk of irritation to your stomach lining and can lead to stomach ulcers or bleeding.

Alimentos (General)

It is recommended to take ibuprofen with food or a glass of milk to reduce the risk of stomach upset or irritation.

Absorción de vitamina B12

El uso prolongado de metformina puede impedir que su cuerpo absorba suficiente vitamina B12 de los alimentos. Es posible que necesite que su médico controle sus niveles de B12 o que tome un suplemento si desarrolla síntomas como fatiga extrema o una lengua dolorida.

Taking multiple medicines? Our Verificador de Interacciones de Medicamentos helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Descargo de responsabilidad

Esta información es solo para fines educativos generales y no debe considerarse como un sustituto del consejo médico profesional. Siempre consulte a su médico de cabecera, farmacéutico u otro profesional de la salud calificado antes de tomar decisiones sobre sus medicamentos. Las circunstancias individuales pueden variar, y solo un profesional de la salud que conozca su historial médico puede proporcionar orientación personalizada.