Can I take Amitriptyline and Colecalciferol together?
Drug interaction guide
Originally published 25 Jan 2026
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There are no known significant interactions between amitriptyline and colecalciferol (Vitamin D3). It is generally considered safe to take these two medications together.
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Why this happens
Amitriptyline is a tricyclic antidepressant that works on brain chemicals, while colecalciferol is a vitamin supplement used to maintain bone health and calcium levels. They are processed by different pathways in the body and do not interfere with how the other works.
What you should do
You can continue to take both medications as prescribed by your doctor. No special precautions or timing adjustments are necessary for this combination.
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Using other medicines
Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Descargo de responsabilidad
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Historia del artículo
La información de esta página ha sido redactada y revisada por médicos cualificados.
25 Enero 2026 | Publicado originalmente
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