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sarcoglycan beta

El SGCB gene provides instructions for making the beta component (subunit) of a group of proteins called the sarcoglycan protein complex. The sarcoglycan protein complex is located in the membrane surrounding muscle cells. It helps maintain the structure of muscle tissue by attaching (binding) to and stabilizing the dystrophin complex, which is made up of proteins called dystrophins and dystroglycans. The large dystrophin complex strengthens muscle fibers and protects them from injury as muscles tense (contract) and relax. It acts as an anchor, connecting each muscle cell's structural framework (cytoskeleton) with the lattice of proteins and other molecules outside the cell (extracellular matrix).

Normal function

El SGCB gene provides instructions for making the beta component (subunit) of a group of proteins called the sarcoglycan protein complex. The sarcoglycan protein complex is located in the membrane surrounding muscle cells. It helps maintain the structure of muscle tissue by attaching (binding) to and stabilizing the dystrophin complex, which is made up of proteins called dystrophins and dystroglycans. The large dystrophin complex strengthens muscle fibers and protects them from injury as muscles tense (contract) and relax. It acts as an anchor, connecting each muscle cell's structural framework (cytoskeleton) with the lattice of proteins and other molecules outside the cell (extracellular matrix).

Conditions referring to this gene or chromosome

Otros nombres

43 kDa dystrophin-associated glycoprotein

43DAG

A3b

beta-sarcoglycan

beta-SG

LGMD2E

sarcoglycan, beta (43kDa dystrophin-associated glycoprotein)

SG-beta

SGC

SGCB_HUMAN

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Lecturas adicionales y referencias

Historial del artículo

La información en esta página está escrita y revisada por pares por clínicos calificados.
  • 19 Nov 2025 | Última versión
  • 1 Feb 2011 | Publicado originalmente

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