Can I take Paracetamol and Simvastatin together?
Drug interaction guide
Originally published 25 Jan 2026
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There is no known significant interaction between paracetamol and simvastatin. It is generally considered safe to take these two medicines together at the recommended doses.
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Why this happens
Paracetamol and simvastatin are processed by different pathways in the liver. Paracetamol does not interfere with how simvastatin is absorbed, broken down, or removed from the body, and vice versa.
What you should do
You can continue to take both medicines as prescribed by your doctor or as directed on the packaging. Always stick to the recommended daily limit for paracetamol (usually no more than eight 500mg tablets in 24 hours for an adult) and avoid excessive alcohol consumption, as both alcohol and simvastatin can affect your liver.
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Using other medicines
Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Descargo de responsabilidad
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Historia del artículo
La información de esta página ha sido redactada y revisada por médicos cualificados.
25 Enero 2026 | Publicado originalmente
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