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Can I take Naproxen and Paracetamol together?

Guía de interacción de medicamentos

It is generally safe to take naproxen and paracetamol together. There is no direct interaction between these two medicines. In fact, doctors often recommend taking them together for short periods if one medicine alone is not providing enough pain relief.

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Por qué sucede esto

Naproxen and paracetamol work in different ways to block pain signals. Naproxen is a non-steroidal anti-inflammatory drug (NSAID) that reduces inflammation, while paracetamol works mainly in the central nervous system. Because they do not interfere with how the body processes (metabolises) each other, they can be used at the same time.

You can take these medicines together, but ensure you do not exceed the maximum daily dose for either. Always take naproxen with food or a milky drink to protect your stomach. If you find you need to take this combination for more than a few days, speak to your pharmacist or GP to ensure there isn't an underlying issue that needs different treatment.

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Asma

Do not take naproxen if you have asthma that is sensitive to aspirin or other NSAIDs, as it can trigger a life-threatening asthma attack or severe breathing difficulties.

Úlceras estomacales o sangrado

Naproxen can cause serious stomach ulcers and internal bleeding. This risk is higher if you have had ulcers before, are over 65, or take other blood-thinning medicines. Stop taking it and see a doctor immediately if you have black, tarry stools or vomit blood.

Liver health and overdose risk

Never exceed the maximum dose of paracetamol. Taking too much can cause fatal liver damage. Check all other cold and flu remedies to ensure they do not also contain paracetamol.

Embarazo (tercer trimestre)

Do not take naproxen if you are more than 20 weeks pregnant. It can cause serious kidney or heart problems in the unborn baby and may lead to complications during delivery.

Alcohol

It is best to avoid or strictly limit alcohol when taking paracetamol. Combining alcohol and paracetamol increases the risk of serious liver damage.

It is best to avoid or strictly limit alcohol while taking naproxen. Both alcohol and naproxen can irritate the lining of your stomach; combining them significantly increases your risk of developing stomach ulcers or internal bleeding.

Alimentos (General)

Debes tomar naproxeno con o justo después de una comida o un refrigerio. Esto ayuda a proteger el revestimiento de tu estómago y reduce el riesgo de indigestión o dolor de estómago.

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Taking multiple medicines? Our Verificador de Interacciones de Medicamentos helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Descargo de responsabilidad

Esta información es solo para fines educativos generales y no debe considerarse como un sustituto del consejo médico profesional. Siempre consulte a su médico de cabecera, farmacéutico u otro profesional de la salud calificado antes de tomar decisiones sobre sus medicamentos. Las circunstancias individuales pueden variar, y solo un profesional de la salud que conozca su historial médico puede proporcionar orientación personalizada.

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Historial del artículo

La información en esta página está escrita y revisada por pares por clínicos calificados.

  • 25 Ene 2026 | Publicado originalmente
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