Can I take Metformin and Clopidogrel together?

Por qué sucede esto

Clopidogrel and metformin are processed by different pathways in the body. Clopidogrel is an antiplatelet medicine that works on blood cells to prevent clots, while metformin works on the liver and muscles to improve insulin sensitivity. They do not interfere with each other's absorption, metabolism, or effectiveness.

You can safely take these two medicines together as prescribed by your doctor. However, always monitor your blood sugar levels regularly and watch for any unusual bruising or bleeding, which are side effects of clopidogrel. If you are scheduled for surgery, ensure your doctor knows you are taking clopidogrel, as it may need to be paused.

Riesgo de sangrado

Clopidogrel thins your blood. You are at a higher risk of serious bleeding. Seek urgent medical help if you have a fall or head injury, or if you notice signs of internal bleeding such as black, tarry stools or vomiting blood. You must tell your surgeon or dentist that you are taking clopidogrel before any procedure, as you may need to stop taking it temporarily to prevent excessive bleeding.

Acidosis láctica

In rare cases, metformin can cause a serious build-up of acid in the blood. Seek immediate medical attention if you experience severe vomiting, stomach ache, muscle cramps, or a general feeling of being very unwell with extreme tiredness.

Severe kidney problems

You must not take metformin if you have severe kidney failure. Your doctor should check your kidney function before you start and at least once a year while taking it.

Deshidratación severa o infección

Si desarrolla vómitos severos, diarrea o fiebre alta, debe suspender temporalmente la metformina y contactar a su médico para prevenir la sobrecarga renal.

Alcohol

It is best to avoid or strictly limit alcohol while taking metformin. Drinking alcohol can increase the risk of a rare but serious condition called lactic acidosis (a build-up of lactic acid in the blood) and can also increase the risk of low blood sugar (hypoglycaemia).

It is best to avoid or strictly limit alcohol while taking clopidogrel. Both alcohol and clopidogrel can irritate the stomach lining and increase the risk of internal bleeding, particularly in the stomach and intestines.

Absorción de vitamina B12

El uso prolongado de metformina puede impedir que su cuerpo absorba suficiente vitamina B12 de los alimentos. Es posible que necesite que su médico controle sus niveles de B12 o que tome un suplemento si desarrolla síntomas como fatiga extrema o una lengua dolorida.

Taking multiple medicines? Our Verificador de Interacciones de Medicamentos helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Descargo de responsabilidad

Esta información es solo para fines educativos generales y no debe considerarse como un sustituto del consejo médico profesional. Siempre consulte a su médico de cabecera, farmacéutico u otro profesional de la salud calificado antes de tomar decisiones sobre sus medicamentos. Las circunstancias individuales pueden variar, y solo un profesional de la salud que conozca su historial médico puede proporcionar orientación personalizada.