Can I take Lansoprazole and Naproxen together?
Guía de interacción de medicamentos
Publicado originalmente 25 Ene 2026
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Lansoprazole is actually often prescribed alongside naproxen to protect your stomach. Naproxen can irritate the stomach lining and cause ulcers, while lansoprazole reduces stomach acid to prevent this damage. However, lansoprazole can slightly change how quickly or how much naproxen is absorbed into your bloodstream.
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Por qué sucede esto
Lansoprazole increases the pH (reduces the acidity) of the stomach. Because naproxen needs a certain level of acidity to dissolve and be absorbed efficiently, the presence of lansoprazole can slightly alter its absorption profile. This is generally considered a 'beneficial' interaction because the protective effect on the stomach outweighs the minor change in drug absorption.
Lo que deberías hacer
Volver al contenidoIt is safe and common to take these together. In fact, if you are taking naproxen long-term, your doctor likely prescribed lansoprazole specifically to prevent stomach ulcers. Take them exactly as directed by your healthcare professional. If you notice any unusual stomach pain or black, tarry stools, contact your doctor immediately.
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Precauciones importantes
Volver al contenidoAsma
Do not take naproxen if you have a history of asthma or wheezing triggered by aspirin or other NSAIDs, as it can cause a life-threatening asthma attack.
Embarazo (tercer trimestre)
Naproxen must not be taken if you are more than 20 weeks pregnant as it can cause serious heart or kidney problems in the unborn baby and reduce amniotic fluid levels.
Úlceras estomacales o sangrado
Naproxen significantly increases the risk of stomach ulcers and bleeding. Lansoprazole is often prescribed alongside it to reduce this risk, so it is vital to take both as directed.
Diarrea severa
Lansoprazole can increase your risk of serious bowel infections. If you develop severe or persistent watery diarrhoea, or a fever, contact your doctor immediately and do not take anti-diarrhoeal medicine.
Lupus (SLE) or skin reactions
Contact your doctor if you develop a skin rash, especially in areas exposed to the sun, as lansoprazole can cause a rare but serious autoimmune skin reaction.
Advertencias sobre alimentos y bebidas
Volver al contenidoAlcohol
It is best to avoid or strictly limit alcohol while taking lansoprazole. Alcohol increases the amount of acid your stomach produces, which can make your symptoms worse and counteract the effects of the medicine.
It is best to avoid or strictly limit alcohol while taking naproxen. Both alcohol and naproxen can irritate the lining of your stomach; combining them significantly increases the risk of stomach ulcers and internal bleeding.
Alimentos (Horario)
Lansoprazole works best if you take it at least 30 minutes before food. Taking it with or after food can make it less effective at reducing stomach acid.
You should take naproxen with or just after a meal or a snack. This helps to protect your stomach lining and reduces the risk of indigestion or stomach pain.
Cafeína (Café, Té, Bebidas Energéticas)
Caffeine can increase stomach acid production and irritate the stomach lining. This may worsen the conditions these medicines are treating (such as acid reflux or stomach sensitivity) and may increase the risk of indigestion.
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Uso de otros medicamentos
Volver al contenido¿Tomas múltiples medicamentos? Nuestro Verificador de Interacciones de Medicamentos te ayuda a verificar si tus recetas, medicamentos de venta libre y suplementos son seguros para tomar juntos. Simplemente busca tus medicamentos para ver posibles interacciones y qué hacer al respecto.
Descargo de responsabilidad
Esta información es solo para fines educativos generales y no debe considerarse como un sustituto del consejo médico profesional. Siempre consulte a su médico de cabecera, farmacéutico u otro profesional de la salud calificado antes de tomar decisiones sobre sus medicamentos. Las circunstancias individuales pueden variar, y solo un profesional de la salud que conozca su historial médico puede proporcionar orientación personalizada.
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Historial del artículo
La información en esta página está escrita y revisada por pares por clínicos calificados.
25 Ene 2026 | Publicado originalmente

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