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Can I take Fluanxol and Venlafaxine together?

Guía de interacción de medicamentos

Taking fluanxol (flupentixol) and venlafaxine together can increase the risk of a rare but serious heart rhythm problem. It may also increase the risk of 'serotonin syndrome' (too much serotonin in the brain) and make you feel more drowsy or dizzy than usual.

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Por qué sucede esto

Both medications can affect the electrical activity of the heart (prolonging the QT interval). Additionally, both drugs influence brain chemicals like serotonin and dopamine, which can lead to additive side effects on the nervous system.

You must speak to your doctor before taking these together. They may want to perform a heart trace (ECG) or blood tests to ensure it is safe for you. Seek immediate medical help if you feel a racing heartbeat, severe dizziness, fainting, or experience muscle twitching and high fever.

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Salud mental y trastornos del estado de ánimo

La venlafaxina puede causar un aumento en los pensamientos suicidas o autolesiones, especialmente al comenzar el tratamiento o al cambiar la dosis. Vigile su estado de ánimo de cerca y busque ayuda médica urgente si nota cambios preocupantes.

Presión arterial alta (Hipertensión)

Venlafaxine can significantly increase your blood pressure. You must have your blood pressure checked before starting treatment and regularly while taking it. If you have uncontrolled high blood pressure, this medicine may not be suitable for you.

enfermedad de Parkinson

Fluanxol can worsen the symptoms of Parkinson's disease and may interfere with the effectiveness of Parkinson's medications. It should generally be avoided if you have this condition.

Trastornos del ritmo cardíaco (Síndrome de QT largo)

Both medicines can affect your heart rhythm, especially if taken together or with other heart medications. Seek immediate medical help if you experience palpitations, fainting, or a very fast heartbeat.

Trastornos de la coagulación

venlafaxine increases your risk of serious bleeding, especially if you are also taking aspirin, ibuprofen, or blood-thinning medications like warfarin.

Abruptly stopping treatment

Never stop taking venlafaxine suddenly. Doing so can cause severe withdrawal symptoms (discontinuation syndrome). Your dose must be reduced very gradually under medical supervision.

Síndrome de serotonina

Taking these medicines together, or with other pro-serotonergic substances, can cause a life-threatening build-up of serotonin. Seek urgent medical help if you experience high fever, agitation, confusion, or severe muscle twitching.

Alcohol

It is best to avoid or strictly limit alcohol while taking these medicines. Both Fluanxol and Venlafaxine can cause drowsiness and dizziness; alcohol will significantly increase these effects, making you more likely to have an accident or fall. Combining alcohol with these medications also increases the risk of liver damage.

Cafeína (Café, Té, Bebidas Energéticas)

Caffeine can interfere with how Fluanxol works. High amounts of caffeine may reduce the effectiveness of the medicine or worsen symptoms of restlessness and anxiety. Try to keep your caffeine intake consistent and moderate.

Venlafaxine can increase your blood pressure and heart rate. High amounts of caffeine can worsen these effects, potentially leading to palpitations, jitteriness, or anxiety. Monitor your intake if you feel these symptoms.

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Taking multiple medicines? Our Verificador de Interacciones de Medicamentos helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Descargo de responsabilidad

Esta información es solo para fines educativos generales y no debe considerarse como un sustituto del consejo médico profesional. Siempre consulte a su médico de cabecera, farmacéutico u otro profesional de la salud calificado antes de tomar decisiones sobre sus medicamentos. Las circunstancias individuales pueden variar, y solo un profesional de la salud que conozca su historial médico puede proporcionar orientación personalizada.

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Historial del artículo

La información en esta página está escrita y revisada por pares por clínicos calificados.

  • 25 Ene 2026 | Publicado originalmente
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