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Can I take Ezetimibe and Vitamin b12 together?

Drug interaction guide

There is no known interaction between ezetimibe and vitamin B12. It is safe to take these two together.

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Why this happens

Ezetimibe works by reducing the amount of cholesterol your body absorbs from food in the small intestine. Vitamin B12 is absorbed through a different pathway and does not interfere with how ezetimibe works. Likewise, ezetimibe does not prevent the body from absorbing or using vitamin B12.

What you should do

You can continue to take both ezetimibe and vitamin B12 as prescribed. No special precautions or timing changes are necessary.

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Important precautions

Enfermedad hepática

You must not take this medicine if you have moderate or severe liver disease. If you are taking it alongside a statin, your doctor will need to perform regular blood tests to check your liver function.

Unexplained muscle pain

Contact your doctor immediately if you experience unexplained muscle pain, tenderness, or weakness. This is especially important if you are taking ezetimibe in combination with a statin, as it can rarely lead to serious muscle breakdown.

Food and drink warnings

Alcohol

Drinking excessive amounts of alcohol for long periods can reduce the amount of Vitamin B12 your body is able to absorb. If you are taking B12 to treat a deficiency, it is best to keep your alcohol intake within the recommended low-risk limits.

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Using other medicines

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Descargo de responsabilidad

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.

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Historia del artículo

La información de esta página ha sido redactada y revisada por médicos cualificados.

  • 25 Enero 2026 | Publicado originalmente
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