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Can I take Aspirin and Quetiapine together?

Guía de interacción de medicamentos

Taking aspirin and quetiapine together may increase your risk of bleeding, particularly in the stomach or gut. It can also increase the risk of feeling dizzy or faint when you stand up.

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Por qué sucede esto

Aspirin thins the blood and can irritate the stomach lining, while quetiapine can sometimes interfere with how platelets (the cells that help blood clot) work. Additionally, both medications can cause a drop in blood pressure when standing, which may lead to dizziness.

You should use this combination with caution. Watch for signs of unusual bleeding, such as easy bruising, dark or 'tarry' stools, or coughing up blood. To avoid dizziness, try to stand up slowly from a sitting or lying position. If you have a history of stomach ulcers, speak to your doctor before taking aspirin.

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Asma

No tome aspirina si tiene antecedentes de asma desencadenada por aspirina u otros medicamentos antiinflamatorios no esteroides (AINEs), ya que puede provocar un ataque de asma potencialmente mortal.

Niños y adolescentes menores de 16 años

Nunca dé aspirina a niños o adolescentes menores de 16 años a menos que sea específicamente recetada por un médico, debido al riesgo del síndrome de Reye, una condición rara pero fatal que afecta el cerebro y el hígado.

Suicidal thoughts and self-harm

Quetiapine can increase the risk of suicidal thoughts or self-harm, particularly in young adults (under 25). You must tell someone you trust or seek medical help immediately if your mood changes or you have thoughts of hurting yourself.

Heart disease (specifically heart rhythm disorders)

Quetiapine can affect your heart rhythm (QT prolongation). This risk is higher if you already have heart disease or take other medicines that affect the heart. Seek immediate medical help if you experience palpitations, fainting, or a racing heartbeat.

Drowsiness and impaired coordination

Quetiapine causes significant drowsiness and can affect your balance. Do not drive or operate machinery until you know how it affects you, and be careful to avoid falls, especially when getting up from a sitting or lying position.

Diabetes and blood sugar control

Quetiapine can cause a significant increase in blood sugar levels, even if you are not diabetic. If you have diabetes, you must monitor your blood sugar more closely as your medication dose may need adjusting.

Alcohol

Drinking alcohol while taking aspirin increases the risk of developing stomach irritation, ulcers, and bleeding in the digestive tract. It is best to limit or avoid alcohol.

It is best to avoid or strictly limit alcohol while taking quetiapine. Combining alcohol with this medicine can significantly increase drowsiness and dizziness, making you more likely to fall or have an accident. Both substances are processed by the liver, and combining them can put extra strain on your system.

Jugo de toronja

You should avoid drinking grapefruit juice or eating grapefruit while taking quetiapine. Grapefruit contains compounds that interfere with how your body breaks down this medicine. This can cause the levels of quetiapine in your blood to rise to potentially dangerous levels, increasing the risk of serious side effects.

Cafeína (Café, Té, Bebidas Energéticas)

La cafeína puede interferir con el funcionamiento de la quetiapina. Puede reducir la efectividad del medicamento o empeorar ciertos efectos secundarios como la inquietud. Si consumes mucha cafeína, habla con tu médico antes de hacer cambios repentinos en tu consumo, ya que esto también puede afectar los niveles de tu medicamento.

Comidas ricas en grasa

Si estás tomando la versión de liberación prolongada (XL) de quetiapina, debes evitar tomarla con una comida muy pesada o alta en grasas. Esto puede hacer que el medicamento se absorba en tu sistema demasiado rápido (conocido como 'liberación de dosis'), lo que aumenta el riesgo de efectos secundarios. Por lo general, es mejor tomarlo sin comida o con un refrigerio ligero.

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Taking multiple medicines? Our Verificador de Interacciones de Medicamentos helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Descargo de responsabilidad

Esta información es solo para fines educativos generales y no debe considerarse como un sustituto del consejo médico profesional. Siempre consulte a su médico de cabecera, farmacéutico u otro profesional de la salud calificado antes de tomar decisiones sobre sus medicamentos. Las circunstancias individuales pueden variar, y solo un profesional de la salud que conozca su historial médico puede proporcionar orientación personalizada.

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Article history

The information on this page is written and peer reviewed by qualified clinicians.

  • 25 Ene 2026 | Originally published
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