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¿Puedo tomar ácido alendrónico y lansoprazol juntos?

Guía de interacción de medicamentos

Tomar lansoprazol puede hacer que el ácido alendrónico sea menos efectivo para fortalecer sus huesos. También existe un riesgo ligeramente mayor de desarrollar ciertos tipos de fracturas óseas (como fracturas de cadera o muñeca) cuando estos dos tipos de medicamentos se usan juntos durante un largo período.

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Por qué sucede esto

Alendronic acid needs a certain level of stomach acid to be absorbed properly. Lansoprazole works by reducing stomach acid, which can interfere with how well the alendronic acid is taken up by your body. Additionally, both drugs can independently affect bone density when used long-term.

You can take these medicines together, but it is vital to follow the specific timing instructions for alendronic acid. Take your alendronic acid first thing in the morning on an empty stomach with a full glass of plain water, at least 30 minutes before taking lansoprazole or eating any food. Your doctor may also monitor your bone density more closely or ensure you have enough calcium and vitamin D.

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Oesophageal abnormalities or inability to stand/sit upright

You must be able to stay fully upright (sitting or standing) for at least 30 minutes after taking alendronic acid Do not take it if you have problems with your food pipe (oesophagus), as it can cause severe irritation or ulcers if it does not pass quickly into the stomach.

Dental health and jaw bone issues (Osteonecrosis)

Alendronic acid can rarely cause bone loss in the jaw. You must maintain good oral hygiene and have a dental check-up before starting treatment. Tell your dentist you are taking a bisphosphonate before any dental procedures.

Severe diarrhoea (C. difficile)

Lansoprazole may slightly increase the risk of severe bacterial diarrhoea. If you develop persistent or watery diarrhoea, or stomach pain, seek medical advice immediately and do not take anti-diarrhoeal medicine without consulting a doctor.

All food and drink (except plain water)

You must take alendronic acid on an empty stomach first thing in the morning. Food, tea, coffee, or juice will stop the medicine from being absorbed by your body. Wait at least 30 minutes after taking it before having your first food or drink of the day.

Dairy products (milk, cheese, yoghurt)

Dairy products are high in calcium, which binds to alendronic acid and prevents it from working. Do not consume dairy for at least 30 minutes after taking your tablet.

Mineral water

Avoid mineral water as it can contain high levels of calcium. Only take your alendronic acid tablet with a full glass of plain tap water.

Food (general)

Lansoprazole works best if taken at least 30 minutes before food. Taking it with or after a meal can slow down its absorption and make it less effective.

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Taking multiple medicines? Our Verificador de Interacciones de Medicamentos helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Descargo de responsabilidad

Esta información es solo para fines educativos generales y no debe considerarse como un sustituto del consejo médico profesional. Siempre consulte a su médico de cabecera, farmacéutico u otro profesional de la salud calificado antes de tomar decisiones sobre sus medicamentos. Las circunstancias individuales pueden variar, y solo un profesional de la salud que conozca su historial médico puede proporcionar orientación personalizada.

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Historial del artículo

La información en esta página está escrita y revisada por pares por clínicos calificados.

  • 25 Ene 2026 | Publicado originalmente
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