Can I take Gabapentin and Omeprazole together?

Por qué sucede esto

Omeprazole reduces the amount of acid in your stomach. Gabapentin relies on certain conditions in the digestive tract to be absorbed properly, and the change in stomach acidity caused by omeprazole can interfere with this process, leading to lower levels of the medication in your bloodstream.

For most people, this interaction is minor and does not require a change in treatment. However, if you notice that your symptoms (like nerve pain) are not as well-controlled after starting omeprazole, speak to your doctor. You may wish to take gabapentin at least two hours apart from your omeprazole dose to minimise any impact on absorption.

Depresión respiratoria

Gabapentin can cause serious breathing difficulties, especially if you have an existing lung condition or take other medicines that cause drowsiness (like opioids). Seek immediate medical help if you experience slow or shallow breathing.

Suicidal ideation

A small number of people taking gabapentin have experienced suicidal thoughts or behaviours. You must monitor your mood closely and contact your doctor immediately if you notice any sudden changes in how you feel.

Abrupt discontinuation

Do not stop taking gabapentin suddenly. Doing so can cause serious side effects, including an increase in seizure frequency or severe withdrawal symptoms. Your dose must be reduced gradually.

Diarrea severa

Contact your doctor immediately if you develop severe or persistent watery diarrhoea, as omeprazole can increase the risk of a serious bowel infection called C. difficile.

Lupus-like skin reactions - omeprazole

Seek medical advice if you develop a skin rash, especially in areas exposed to the sun, as this may be a sign of subacute cutaneous lupus erythematosus (SCLE).

Masking symptoms of gastric cancer

Omeprazole can hide the symptoms of more serious stomach conditions. You must tell your doctor if you experience unexplained weight loss, persistent vomiting, or difficulty swallowing while taking this medicine.

Alcohol

Drinking alcohol while taking gabapentin can increase the risk of side effects, such as extreme sleepiness, dizziness, and difficulty concentrating. It is best to avoid or strictly limit alcohol until you know how the medicine affects you.

It is best to avoid or strictly limit alcohol while taking omeprazole. Alcohol can increase the amount of acid your stomach produces, which may worsen your symptoms or make the medicine less effective. Additionally, both alcohol and omeprazole can irritate the stomach lining.

Caffeine (Coffee, Tea, Cola)

While there is no direct chemical interaction, caffeine can increase stomach acid production. Since omeprazole is used to reduce stomach acid, consuming high amounts of caffeine may counteract the benefits of the medicine and worsen your symptoms.

¿Tomas múltiples medicamentos? Nuestro Verificador de Interacciones de Medicamentos te ayuda a verificar si tus recetas, medicamentos de venta libre y suplementos son seguros para tomar juntos. Simplemente busca tus medicamentos para ver posibles interacciones y qué hacer al respecto.

Descargo de responsabilidad

Esta información es solo para fines educativos generales y no debe considerarse como un sustituto del consejo médico profesional. Siempre consulte a su médico de cabecera, farmacéutico u otro profesional de la salud calificado antes de tomar decisiones sobre sus medicamentos. Las circunstancias individuales pueden variar, y solo un profesional de la salud que conozca su historial médico puede proporcionar orientación personalizada.