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¿Puedo tomar Diazepam y Codeína juntos?

Guía de interacción de medicamentos

Taking diazepam and codeine together can cause extreme sleepiness, dizziness, and severe breathing difficulties. In serious cases, this combination can lead to a coma or be life-threatening because it can cause you to stop breathing.

Por qué sucede esto

Both medicines are 'central nervous system depressants'. This means they both slow down brain activity and the signals that tell your body to breathe. When taken together, their effects add up, making the impact on your breathing and alertness much stronger than if taken alone.

Lo que deberías hacer

You should only take these two medicines together if they have been specifically prescribed by the same doctor who is aware you are taking both. If you must take both, use the lowest dose possible for the shortest amount of time. Seek emergency medical help immediately if you experience extreme sleepiness, shallow breathing, or difficulty staying awake. Avoid alcohol completely while taking these medicines.

Precauciones importantes

Combined use with other sedatives or alcohol

Taking these medicines together, or with alcohol, significantly increases the risk of life-threatening breathing problems and extreme sleepiness. Avoid alcohol and do not take other sedating medicines unless specifically directed by your doctor.

Ultra-rapid metabolism (CYP2D6)

Some people turn codeine into morphine much faster than normal. If you experience extreme sleepiness, confusion, or shallow breathing, stop taking the medicine and seek urgent medical help. This is especially dangerous for breastfeeding mothers as it can cause fatal overdose in the baby.

Long-term use and dependence

These medicines are for short-term use only. Taking them for more than a few days can lead to physical addiction and withdrawal symptoms when you stop. Do not increase the dose or take them for longer than prescribed.

Asma o problemas respiratorios

No tome codeína si tiene asma severa o dificultades para respirar, ya que puede disminuir peligrosamente su respiración.

Conducción y operación de maquinaria

It is often an offence to drive while taking diazepam as it can seriously impair your coordination and reaction times. Do not drive or operate machinery until you know how this medicine affects you, and always keep the medicine in its original packaging to show the police if stopped.

Depresión respiratoria

No tome diazepam si tiene una enfermedad pulmonar grave o dificultades para respirar, ya que puede ralentizar aún más su respiración a niveles peligrosos.

Embarazo

Evite su uso en el final del embarazo o durante el parto, ya que puede causar 'síndrome del bebé hipotónico' y síntomas de abstinencia potencialmente mortales en el recién nacido.

Advertencias sobre alimentos y bebidas

Alcohol

You must avoid drinking alcohol while taking these medicines. Both diazepam and codeine cause drowsiness and slow down your breathing. Alcohol significantly increases these effects, which can lead to dangerous levels of sedation, breathing difficulties, and loss of consciousness.

Jugo de toronja

Avoid drinking large amounts of grapefruit juice. Grapefruit contains compounds that can stop your body from breaking down diazepam properly. This can lead to higher levels of the medicine in your blood, increasing the risk of side effects like extreme sleepiness and poor coordination.

Cafeína (Café, té, bebidas energéticas)

Caffeine is a stimulant and can have the opposite effect of diazepam, which is a sedative. Consuming high amounts of caffeine may make diazepam less effective at treating anxiety or helping you sleep.

Uso de otros medicamentos

¿Tomas múltiples medicamentos? Nuestro Verificador de Interacciones de Medicamentos te ayuda a verificar si tus recetas, medicamentos de venta libre y suplementos son seguros para tomar juntos. Simplemente busca tus medicamentos para ver posibles interacciones y qué hacer al respecto.

Descargo de responsabilidad

Esta información es solo para fines educativos generales y no debe considerarse como un sustituto del consejo médico profesional. Siempre consulte a su médico de cabecera, farmacéutico u otro profesional de la salud calificado antes de tomar decisiones sobre sus medicamentos. Las circunstancias individuales pueden variar, y solo un profesional de la salud que conozca su historial médico puede proporcionar orientación personalizada.

Historial del artículo

La información en esta página está escrita y revisada por pares por clínicos calificados.
  • 25 Ene 2026 | Publicado originalmente

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