Can I take Amitriptyline and Esomeprazole together?

Por qué sucede esto

Amitriptyline is broken down in the liver by specific proteins (enzymes). Esomeprazole can slow down the activity of these proteins, which means the amitriptyline stays in your system longer and reaches higher levels than intended.

You can take these medicines together, but you should be aware of the potential for increased side effects. If you feel unusually drowsy, dizzy, or notice your heart racing, speak to your doctor. They may decide to adjust your dose of amitriptyline.

Pensamientos y comportamientos suicidas

Amitriptyline can increase thoughts of self-harm or suicide, particularly when first starting treatment or changing doses. Seek immediate medical help if your mood changes or you have distressing thoughts.

Glaucoma (specifically acute angle-closure glaucoma

Do not take amitriptyline if you have a history of narrow-angle glaucoma, as it can cause a sudden, dangerous increase in eye pressure.

Severe bacterial diarrhoea (C. difficile)

Esomeprazole reduces stomach acid, which can increase your risk of serious gut infections. Seek medical advice if you develop severe or persistent watery diarrhoea, stomach pain, and fever.

Alcohol

Beber alcohol mientras tomas amitriptilina puede hacerte sentir muy somnoliento e inestable al caminar. Es mejor evitar el alcohol, especialmente cuando comienzas el tratamiento o si tu dosis se incrementa.

Cafeína (Café, Té, Bebidas Energéticas)

Amitriptyline can sometimes cause a fast or irregular heartbeat. High intake of caffeine can worsen these side effects and may also interfere with the sedative effect of the medicine.

Taking multiple medicines? Our Verificador de Interacciones de Medicamentos helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Descargo de responsabilidad

Esta información es solo para fines educativos generales y no debe considerarse como un sustituto del consejo médico profesional. Siempre consulte a su médico de cabecera, farmacéutico u otro profesional de la salud calificado antes de tomar decisiones sobre sus medicamentos. Las circunstancias individuales pueden variar, y solo un profesional de la salud que conozca su historial médico puede proporcionar orientación personalizada.