Teofilina
Uniphyllin Continus
Revisado por pares por Sid DajaniÚltima actualización por Michael Stewart, MRPharmSLast updated 12 Oct 2022
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Theophylline helps relieve symptoms such as cough, wheeze and shortness of breath.
Make sure that you receive the same brand of theophylline each time you collect your prescription.
Swallow the tablets whole - do not crush or chew them.
If you are a smoker or drink alcohol, ask your doctor for advice, as these can affect the levels of theophylline in your blood.
At a glance
Theophylline is a medicine for lung problems like asthma and COPD, and sometimes heart failure.
It opens up airways in your lungs, making breathing easier.
Always stick to the same brand of theophylline as amounts absorbed can vary.
It is usually taken twice a day, every 12 hours.
Tell your doctor or pharmacist about other conditions or medicines you are taking.
If your symptoms get worse, contact a doctor or nurse straightaway.
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About theophylline
Tipo de medicamento | Xanthine bronchodilator |
Usado para | Lung-related problems such as asthma and chronic obstructive pulmonary disease (COPD); sometimes used to treat heart failure |
También llamado | Uniphyllin Continus® |
Disponible como | Modified-release tablets |
Theophylline is an oral bronchodilator medicine which is prescribed for people with breathing problems, such as asma y enfermedad pulmonar obstructiva crónica (EPOC). It is a medicine that you take by mouth, as a tablet or capsule.
Theophylline works by opening up the air passages in your lungs so that air can flow into your lungs more freely. This makes breathing easier and helps relieve symptoms such as coughing, wheezing and shortness of breath.
It is important always to stick to the same brand of theophylline. This is because the amount of theophylline absorbed by your body varies greatly between brands. If you start taking a different brand to the one you normally have, you may be getting too much or too little theophylline.
Before taking theophylline
Volver al contenidoSome medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking theophylline it is important that your doctor or pharmacist knows:
Si estás embarazada, intentando tener un bebé o amamantando.
If you have a heart condition or have had a heart attack.
Si tienes problemas renales o hepáticos.
Si tienes una glándula tiroides hiperactiva (hipertiroidismo).
Si tienes presión arterial alta.
If you have a stomach ulcer.
If you drink alcohol, or smoke.
Si tienes epilepsia.
If you are currently unwell with a high temperature (fever).
Si tienes un trastorno sanguíneo hereditario raro llamado porfiria.
If you have been told you have low levels of potassium in your blood.
If you are taking or using any other medicines or inhalers. This includes any medicines you are taking which are available to buy without a prescription, as well as herbal and complementary medicines.
Si alguna vez has tenido una reacción alérgica a un medicamento.
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How to take theophylline
Volver al contenidoBefore starting this treatment, read the manufacturer's printed information leaflet from inside the pack. The leaflet will give you more information about theophylline and a full list of side-effects which you may experience from taking it.
Theophylline is usually taken twice a day, although some doctors may prescribe just one dose a day. Take the tablets exactly as your doctor tells you to.
For twice daily doses, always try to take your doses 12 hours apart and at the same times each day. For example, at 8 am and 8 pm each day.
Your dose may be adjusted over the first few weeks depending on the results of some blood tests. This allows your doctor to make sure that you have the dose that helps your condition and avoids any unwanted symptoms. Your doctor or pharmacist will explain to you the directions for taking your doses, and this information will also be printed on the label of the pack of tablets to remind you.
You should swallow the tablets whole with a drink of water. Do not crush or chew the tablets.
If you forget to take a dose, leave out the missed dose and take the next dose at the normal time. Do not take two doses together to make up for a forgotten dose.
Obteniendo el máximo de tu tratamiento
Volver al contenidoContinue to take theophylline unless your doctor tells you otherwise. Bronchodilators like theophylline are usually prescribed long-term.
Try to keep your regular appointments with your doctor. This is so your doctor can review your condition on a regular basis. Your doctor will want to test your blood from time to time to make sure that you are receiving the correct dose and also to check the levels of potassium in your blood.
The amount of theophylline in your blood should be kept within a certain range. It can vary if you are unwell, or if you start or stop smoking, take other medicines, or drink more alcohol than usual. This is because these things interfere with the way theophylline is handled by your body. Some of these things will increase the amount of theophylline in your body, leading to side-effects. Others will reduce it, leading to your treatment not being as effective as it should be.
If at any time you find that your symptoms are getting worse, contact a doctor or nurse for advice straightaway.
If you want to buy any medicines, check with a pharmacist that they are safe for you to take. Some medicines (including the herbal remedy St John's wort) can affect the levels of theophylline in your blood and should not be taken alongside it without your doctor knowing.
Some vaccines, such as the flu vaccine, may also affect theophylline levels. Make sure you tell your doctor about any vaccinations you have.
If you are due to have an operation or any dental treatment, tell the person carrying out the treatment which medicines you are taking, as some anaesthetics can interfere with theophylline.
Theophylline can be very toxic in overdose. If you suspect that someone has taken more than they should (and especially if it is a child), go to the accident and emergency department of your local hospital straightaway. Take the container with you, even if it is empty.
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Can theophylline cause problems?
Volver al contenidoAlong with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with theophylline. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following side-effects continue or become troublesome.
Común theophylline side-effects | ¿Qué puedo hacer si experimento esto? |
Feeling sick (nausea), upset stomach | Stick to simple foods - avoid rich or spicy meals. Try taking your doses after meals |
A fast heartbeat, difficulty sleeping, feeling shaky or dizzy, being sick (vomiting) | If these symptoms continue or are severe, speak with your doctor or pharmacist, as they could be signs your dose is too high |
Dolor de cabeza | Bebe mucha agua y pide a tu farmacéutico que te recomiende un analgésico adecuado. Si los dolores de cabeza continúan, informa a tu médico |
Si experimenta otros síntomas que cree que pueden deberse a este medicamento, hable con su médico o farmacéutico.
How to store theophylline
Volver al contenidoMantenga todos los medicamentos fuera del alcance y la vista de los niños.
Almacenar en un lugar fresco y seco, lejos del calor y la luz directos.
Información importante sobre todos los medicamentos
Volver al contenidoInformación importante sobre todos los medicamentos
Never take more than the prescribed dose. If you suspect that you or someone else might have taken an overdose of this medicine, go to the accident and emergency department of your local hospital at once. Take the container with you, even if it is empty, so the doctor knows what has been taken.
Este medicamento es para ti. Nunca lo des a otras personas, incluso si su condición parece ser la misma que la tuya.
No guardes medicamentos caducados o no deseados. Llévalos a tu farmacia local, que se encargará de desecharlos por ti.
Si tienes alguna pregunta sobre este medicamento, consulta a tu farmacéutico.
Informar efectos secundarios de un medicamento o vacuna
Si experimenta efectos secundarios, puede reportarlos en línea a través de Yellow Card website.

¿Inseguro sobre mezclar medicamentos?
Verifica posibles interacciones entre medicamentos, suplementos y alimentos antes de tomarlos juntos.
Preguntas frecuentes
What type of conditions does theophylline help with?
Theophylline is prescribed to treat lung-related problems such as asthma and chronic obstructive pulmonary disease (COPD). It is also sometimes used in the treatment of heart failure.
How does theophylline help me to breathe better?
Theophylline is a bronchodilator medicine. It works by opening up the air passages in your lungs, allowing air to flow more freely. This action makes breathing easier and helps to reduce symptoms like coughing, wheezing, and shortness of breath.
Why is it important to always use the same brand of theophylline?
The amount of theophylline absorbed by your body can differ significantly between different brands. If you switch brands, you might get too much or too little of the medicine, which could affect its effectiveness or lead to side-effects.
What should I do if I forget to take a dose of theophylline?
If you miss a dose, you should skip that dose completely and take your next dose at the usual scheduled time. Do not take two doses together to make up for the one you missed.
Can taking other medicines or making lifestyle changes affect my theophylline treatment?
Yes, various factors can affect the amount of theophylline in your blood. Being unwell, starting or stopping smoking, taking other medicines (including over-the-counter and herbal remedies like St John's wort), drinking more alcohol than usual, and even some vaccines (like the flu vaccine) can all interfere with how your body handles theophylline. These changes can either increase the amount of theophylline, potentially causing side-effects, or decrease it, making the treatment less effective.
What should I do if my breathing symptoms get worse while taking theophylline?
If you find that your breathing symptoms are getting worse at any point, you should contact a doctor or nurse for advice straightaway.
What are some common side-effects of theophylline and what can I do about them?
Common side-effects include feeling sick (nausea) or an upset stomach. For these, try eating simple foods, avoiding rich or spicy meals, and taking your doses after food. If you experience a fast heartbeat, difficulty sleeping, shakiness, dizziness, or vomiting, these could be signs your dose is too high, and you should speak with your doctor or pharmacist if they continue or are severe. For headaches, drink plenty of water and ask a pharmacist for a suitable painkiller. If headaches persist, let your doctor know.
Lecturas adicionales y referencias
- Manufacturer's PIL, Uniphyllin Continus® 200 mg, 300 mg and 400 mg Tablets; Napp Pharmaceuticals Ltd, The electronic Medicines Compendium. Dated January 2019.
- Medicamentos Completos BNF 89ª Edición; Asociación Médica Británica y Sociedad Real de Farmacia de Gran Bretaña, Londres.
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About the authorView full bio

Michael Stewart, MRPharmS
Medicine Leaflet Review Manager – Contractor, Pharmacist
BPharm (Hons), MRPharmS
Michael is a community pharmacist practicing in the Midlands and South Yorkshire with more than 20 years’ experience advising on medicines and medical conditions. He has a strong background in healthcare training, having produced and delivered training courses for pharmacy teams and staff of residential care settings, including nurses. He has also contributed to pharmacy advisory boards for the management of low acuity conditions in the community.
About the reviewer

Sid Dajani
Sultan Dajani qualified at the London School of Pharmacy in 1994 and became the youngest elected member of the Royal Pharmaceutical Society council since its founding in 1842.
Historial del artículo
La información en esta página está escrita y revisada por pares por clínicos calificados.
Next review due: 10 Apr 2027
12 Oct 2022 | Última versión

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