Pomada de tacrolimus
Protopic
Revisado por Sid DajaniÚltima actualización por Michael Stewart, MRPharmSÚltima actualización: 14 de agosto de 2023
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Tacrolimus ointment is for external use only and should be applied thinly to affected area(s) of skin.
Do not apply the ointment to any areas of skin which could be infected.
Expect to see an improvement within one week of using the ointment and then continue to use it for a few more weeks until the eczema has cleared.
No beba alcohol, ya que puede enrojecer o ruborizar la piel (sobre todo la de la cara) y provocar sensación de calor.
En este artículo:
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About tacrolimus ointment
Tipo de medicamento | A topical immunomodulator |
Utilizado para | Moderate-to-severe eczema in adults or in children over 2 years of age |
También llamado | Protopic® |
Disponible como | Pomada |
Tacrolimus ointment helps reduce inflammatory skin reactions. It is prescribed for people with moderate-to-severe eczema, usually as an alternative to other treatments such as steroid creams or ointments. It is applied topically (on to the skin) to reduce symptoms such as inflammation, redness and itching. Tacrolimus ointment is available in two strengths: 0.03% and 0.1%. Only the lower, 0.03% strength, is suitable for use by children. It will be prescribed initially by a skin specialist doctor.
Tacrolimus is also available as a medicine which is taken by mouth, but this is prescribed for a completely different medical condition. There is a separate information leaflet available about this, called Tacrolimus to prevent organ rejection.
Before using tacrolimus ointment
Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start using tacrolimus ointment it is important that your doctor knows:
Si está embarazada, esperando un bebé o en período de lactancia.
If you have any other skin conditions.
Si tiene los ganglios linfáticos inflamados o el sistema inmunitario debilitado.
Si tiene problemas con el funcionamiento del hígado.
Si alguna vez ha tenido una reacción alérgica a un medicamento, especialmente si fue a un antibiótico macrólido (como eritromicina, claritromicina, azitromicina o telitromicina).
Si toma o utiliza otros medicamentos. Esto incluye cualquier medicamento que esté tomando y que pueda adquirirse sin receta, así como medicamentos a base de plantas y complementarios.
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How to use tacrolimus ointment?
Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about the ointment and will provide you with a full list of the side-effects which you may experience from using it.
Apply a thin layer of ointment to the commonly affected areas of your skin twice daily (it is usually recommended that you apply it morning and evening). It can be applied to most areas of skin on your body, but do not apply it to areas such as your lips, the inside of your nose, or near to your eyes. Do not apply it to any area of skin that could be infected. Remember to wash your hands well with soap and water after using the ointment unless you are treating your hands.
If you forget to apply the ointment, apply it as soon as you remember and then continue as before.
Aproveche al máximo su tratamiento
Procure acudir a las citas periódicas con su médico. Así podrá comprobar su evolución.
Continue to use the ointment until your eczema has cleared. You should expect to see some improvement to your skin within one week of using the ointment, and it should be free from flares within a few more weeks. During this time, your doctor may ask you to reduce how often you apply the ointment or may reduce the strength of the ointment you are using.
Tacrolimus ointment is intended to be used for a short period of time (up to six weeks). It should not be used every day over a long period of time. Some people who frequently have flares may be prescribed the ointment to use on two days of each week to prevent further flares from developing. When it is used like this to prevent flares, there should be at least 2-3 days between applications.
You may continue to use moisturising creams and lotions whilst you are being treated with tacrolimus, but you should wait for at least two hours after you have applied tacrolimus ointment before applying them.
It is important that you don't cover any area of skin treated with tacrolimus with any dressings or bandages. This is because more of the medicine may be absorbed by your skin than is intended.
No beba alcohol porque puede provocar enrojecimiento de la piel y la cara y sensación de calor.
Your doctor will discuss with you the possibility of a slightly increased risk of cancer (particularly skin cancer) associated with medicines like tacrolimus. To help reduce this risk, do not use sunbeds, and avoid strong sunlight. On bright days, even if it is cloudy, use a sun cream with a high sun protection factor (an SPF of at least 15).
If there is no improvement in your skin after using tacrolimus ointment for two weeks, you should see your doctor again for further advice.
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Can tacrolimus ointment cause problems?
Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with tacrolimus ointment. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.
Muy común tacrolimus ointment side-effects (these affect more than 1 in 10 people) | ¿Qué puedo hacer si me ocurre esto? |
A burning sensation, itching | These symptoms generally disappear within one week |
Común tacrolimus ointment side-effects (these affect fewer than 1 in 10 people) | ¿Qué puedo hacer si me ocurre esto? |
Redness, a feeling of warmth, pain, increased skin sensitivity to heat and cold, tingling, rash, local skin infections, cold sores | If any continue or become troublesome, speak with your doctor |
If you experience any other symptoms which you think may be due to the ointment, speak with your doctor or pharmacist for further advice.
How to store tacrolimus ointment?
Mantenga todos los medicamentos fuera del alcance y de la vista de los niños.
Almacenar en un lugar fresco y seco, lejos del calor y la luz directos.
Información importante sobre todos los medicamentos
Información importante sobre todos los medicamentos
Si va a someterse a una operación o a un tratamiento dental, comunique a la persona que lleve a cabo el tratamiento qué medicamentos está utilizando.
Este medicamento es para usted. Nunca se lo dé a otras personas aunque su enfermedad parezca ser la misma que la suya.
The ointment is for use on the skin only. If you suspect that someone has swallowed some of it, go to the accident and emergency department of your local hospital. Take the container with you, even if it is empty.
No guarde medicamentos caducados o que no desee. Llévelos a su farmacia local, que se encargará de eliminarlos por usted.
Si tiene cualquier duda sobre este medicamento pregunte a su farmacéutico.
Informar de los efectos secundarios de un medicamento o vacuna
Si experimenta efectos secundarios, puede notificarlos en línea a través del sitio web de la Tarjeta Amarilla.
Lecturas complementarias y referencias
- Manufacturer's PIL, Protopic® 0.1% Ointment; Leo Laboratories Ltd, The electronic Medicines Compendium. Dated June 2021.
- Manufacturer's PIL, Protopic® 0.03% ointment; Leo Laboratories Ltd, The electronic Medicines Compendium. Dated June 2021.
- Medicamentos BNF completa 89ª edición; Asociación Médica Británica y Real Sociedad Farmacéutica de Gran Bretaña, Londres.
Historia del artículo
La información de esta página ha sido redactada y revisada por médicos cualificados.
Fecha de la próxima revisión: 13 de agosto de 2026
14 ago 2023 | Última versión

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