Omeprazol para reducir el ácido estomacal
Losec, Mezzopram, Prilosec
Revisado por pares por Sid DajaniÚltima actualización por Michael Stewart, MRPharmSÚltima actualización 7 Ago 2023
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Omeprazole reduces the amount of acid produced in the stomach.
Common side effects include stomach upset and headache. These effects are generally mild and do not last long.
Some omeprazole capsules and tablets should be swallowed whole; others can be mixed with water or fruit juice to make swallowing easier - check the manufacturer's printed information leaflet from inside the pack for directions.
De un vistazo
Omeprazole is a proton pump inhibitor used to reduce stomach acid.
It treats conditions like acid reflux, stomach ulcers, and H. pylori infection.
It works by stopping cells in the stomach lining from producing too much acid.
Common side effects include nausea, vomiting, stomach ache, and headache.
Short courses can be bought for reflux symptoms; otherwise, it is prescription-only.
Do not stop taking omeprazole suddenly as symptoms may worsen.
About omeprazole
Tipo de medicamento | Inhibidor de la bomba de protones |
Usado para | Healing or prevention of gastric or duodenal ulcers; gastro-oesophageal reflux disease; Helicobacter pylori infection; Zollinger-Ellison syndrome; acid-related dyspepsia; reduction of gastric acid during surgery |
También llamado (Reino Unido) | Losec®; Mezzopram®; Pyrocalm Control® |
También llamado (EE.UU.) | Prilosec® |
Disponible como | Capsules, tablets, dispersible tablets and injection |
What is omeprazole used for?
Omeprazole is a inhibidor de la bomba de protones (IBP) used to reduce the amount of acid in your stomach. It is usually prescribed for the treatment of digestive conditions such as reflujo ácido y úlceras estomacales.
Omeprazole is also given as one part of a treatment to get rid of Helicobacter pylori, una bacteria que se encuentra en el estómago, la cual puede causar úlceras.
Omeprazole is available on prescription. You can also buy short courses of omeprazole at a pharmacy for the treatment of reflux symptoms (such as heartburn) in adults.
How does omeprazole work?
Omeprazole works by stopping cells in the lining of the stomach from producing too much acid. This can help to prevent ulcers from forming, or assist the healing process where damage has already occurred.
By decreasing the amount of acid, they can also help to reduce the symptoms of acid reflux disease, such as heartburn.
Side effects of omeprazole
The most common side effects of omeprazole are:
Sentirse mal (náuseas).
Estar enfermo (vómitos).
Dolor de estómago.
Farting.
Diarrea.
Estreñimiento.
Dolor de cabeza.
Encontrará una lista completa en el prospecto informativo del fabricante que se suministra con su medicamento.
Los efectos no deseados a menudo mejoran a medida que su cuerpo se adapta al nuevo medicamento, pero hable con su médico o farmacéutico si alguno de los siguientes persiste o se vuelve problemático.
How to manage omeprazole side effects
Common omeprazole side effects (these affect fewer than 1 in 10 people) | ¿Qué puedo hacer si experimento esto? |
Stomach upset, such as feeling sick, stomach ache, or wind (flatulence); tummy (abdominal) pain, being sick | Stick to simple meals - avoid rich or spicy foods. If symptoms are severe or do not go away, let your doctor know |
Diarrea | Bebe mucha agua. Si persiste o se vuelve grave, informa a tu médico |
Estreñimiento | Intenta comer una dieta equilibrada y beber varios vasos de agua cada día |
Dolor de cabeza | Drink plenty of water and ask your pharmacist to recommend a suitable painkiller. If the headaches continue let your doctor know |
Si experimenta otros síntomas que cree que pueden deberse al medicamento, hable con su médico o farmacéutico para obtener más consejos.
Who should not take omeprazole?
Some medicines are not suitable for people with certain conditions. Before taking omeprazole let your doctor know about any of the following:
Si estás embarazada, intentando tener un bebé o amamantando.
Si tienes alguno de los siguientes síntomas: dificultad para tragar, pérdida de sangre, pérdida de peso, o si estás vomitando.
Si tienes algún problema con el funcionamiento de tu hígado.
Si alguna vez has tenido una reacción alérgica a un medicamento.
Si está tomando otros medicamentos. Esto incluye cualquier medicamento que esté tomando y que esté disponible para comprar sin receta, así como medicamentos herbales y complementarios.
How to take omeprazole
Read the manufacturer's printed information leaflet from inside the pack. It will give you more information about omeprazole and will provide you with a full list of the side effects which you may experience from taking it.
Omeprazole tablets and capsules contain small pellets which are specially coated to make sure that the medicine is absorbed correctly by your body. Do not chew the pellets. If you find capsules or tablets difficult to swallow, let your doctor know.
Some omeprazole capsules and tablets can be mixed with water or fruit juice to make swallowing easier and your doctor can prescribe these for you.
Omeprazole can be taken before or after food, although taking it before food can be preferable.
Dosage
If you have bought omeprazole for reflux symptoms such as heartburn, take one or two (10 mg) tablets daily, preferably in a morning. You may need to take omeprazole for a day or so to control your symptoms. If your symptoms do not improve within this time, you should talk to your doctor about this.
Swallow the tablet with a drink of water - do not chew or crush the tablet before you swallow. Do not take omeprazole for more than four weeks without speaking with a doctor.
If you have been prescribed omeprazole, take it exactly as your doctor tells you to. There are different strengths of tablets and capsules available so your doctor will tell you which is right for you. It is usually taken once a day.
If you are taking it for either Helicobacter pylori eradication or for Zollinger-Ellison syndrome, it is likely you will be asked to take two doses a day. Your doctor will tell you which dose is right for you and the directions will also be on the label of the pack to remind you.
Missed dose
If you forget to take a dose at your usual time, you can take it when you remember (unless it is nearly time for your next dose, in which case leave out the missed dose).
No tome dos dosis juntas to make up for a forgotten dose.
Obteniendo el máximo de tu tratamiento
Try to keep your regular appointments with your doctor. This is so your progress can be checked. If you are taking omeprazole on a long-term basis your doctor will want to review your treatment at least once a year to make sure it is still right for you.
A typical course of treatment lasts for one or two weeks if you are taking omeprazole for Helicobacter pylori eradication. It will last for one or two months if it is to allow an ulcer to heal. For all other reasons for taking omeprazole, your treatment will last for as long as is necessary to control your symptoms.
Some foods may make your symptoms worse. Foods and drinks that have been suspected of this include peppermint, tomatoes, chocolate, spicy foods, hot drinks, coffee, and alcoholic drinks.
If it seems that a food is aggravating your symptoms, try avoiding it for a while to see if your symptoms improve.
Also, try avoiding eating large meals, as these can make your symptoms worse too.
Si tienes sobrepeso, ejerce presión adicional sobre tu estómago y fomenta los síntomas del reflujo ácido. Perder algo de peso y seguir una dieta equilibrada y saludable puede ayudarte.
Fumar aumenta la cantidad de ácido producido por el estómago y puede empeorar sus síntomas. Si usted es fumador, hable con su médico o farmacéutico sobre cómo dejar de fumar.
Recent studies suggest that there may be a slight increase in the risk of bone fractures when proton pump inhibitors like omeprazole are taken for longer than a year. If this affects you, your doctor will check that you are taking enough vitamin D and calcium to reduce this risk.
If you buy any medicines 'over the counter', always check with a pharmacist that they are safe to take alongside your other medicines.
How to store omeprazole
Mantenga todos los medicamentos fuera del alcance y la vista de los niños.
Almacenar en un lugar fresco y seco, lejos del calor y la luz directos.
Información importante sobre todos los medicamentos
Información importante sobre todos los medicamentos
Nunca tome más de la dosis prescrita. Si sospecha que usted u otra persona podría haber tomado una sobredosis de este medicamento, acuda al departamento de accidentes y emergencias de su hospital local. Lleve el envase con usted, incluso si está vacío.
Este medicamento es para ti. Nunca lo des a otras personas, incluso si su condición parece ser la misma que la tuya.
Si vas a someterte a una operación o a un tratamiento dental, informa a la persona que realiza el tratamiento sobre los medicamentos que estás tomando.
No guardes medicamentos caducados o no deseados. Llévalos a tu farmacia local, que se encargará de desecharlos por ti.
Si tienes alguna pregunta sobre este medicamento, consulta a tu farmacéutico.
Informar efectos secundarios de un medicamento o vacuna
Si experimenta efectos secundarios, puede reportarlos en línea a través de Sitio web de Yellow Card.
Preguntas frecuentes
How long does omeprazole take to work?
Omeprazole usually starts to work within a few hours, but it can take 1 to 4 days to notice relief from heartburn, acid reflux, stomach ulcers, or GERD. How long it takes to fully work depends on what the condition is.
Is it safe to take omeprazole during pregnancy?
Omeprazole is generally considered safe to take during pregnancy for the treatment of heartburn or acid reflux. However, it’s best to speak with your doctor or midwife before taking it to make sure it’s the right option for you and to get the correct dose.
What should be avoided when taking omeprazole?
When taking omeprazole, avoid alcohol, smoking, and spicy, fatty, or acidic foods. You should also avoid taking omeprazole with certain medicines, such as antifungals, antivirals, or blood thinners, unless your doctor advises otherwise.
What happens if I suddenly stop taking omeprazole?
If you suddenly stop taking omeprazole, your stomach may produce more acid than before, causing your symptoms to return or worsen. This is known as acid rebound and can lead to heartburn, indigestion, or acid reflux. You should reduce your dose gradually to prevent symptoms from coming back.

¿Inseguro sobre mezclar medicamentos?
Verifica posibles interacciones entre medicamentos, suplementos y alimentos antes de tomarlos juntos.
Preguntas frecuentes
Can I take omeprazole if I have difficulty swallowing or other specific symptoms?
You should inform your doctor if you experience symptoms such as difficulty swallowing, loss of blood, unexplained weight loss, or persistent vomiting. These symptoms may mean that omeprazole is not suitable for you, or your doctor may need to investigate further before prescribing.
What if I miss a dose of omeprazole?
If you forget to take a dose at your usual time, you can take it when you remember. However, if it is almost time for your next scheduled dose, you should skip the missed dose and continue with your regular dosing schedule. Do not take two doses at once to make up for a forgotten dose.
How long will I need to take omeprazole?
The duration of your omeprazole treatment depends on the condition being treated. For Helicobacter pylori eradication, a typical course is one to two weeks. If it's for healing an ulcer, treatment usually lasts one to two months. For other conditions, you will take omeprazole for as long as needed to control your symptoms.
Does smoking affect omeprazole's effectiveness or my condition?
Smoking increases the amount of acid produced by the stomach, which can worsen symptoms of acid reflux and other related conditions. If you are a smoker, discussing quitting with your doctor or pharmacist may help improve your symptoms while taking omeprazole.
Are there any long-term risks associated with taking omeprazole?
Recent studies suggest that taking proton pump inhibitors like omeprazole for longer than a year may slightly increase the risk of bone fractures. If you are taking omeprazole long-term, your doctor will likely check that you are getting enough vitamin D and calcium to help reduce this risk.
How should I dispose of old or unwanted omeprazole?
Do not keep out-of-date or unwanted medicines at home. You should take them to your local pharmacy, which will dispose of them for you safely and responsibly.
Lecturas adicionales y referencias
- Manufacturer's PIL, Losec® Capsules 10 mg, 20 mg and 40 mg; Neon Healthcare Ltd, The electronic Medicines Compendium. Dated March 2023.
- Manufacturer's PIL, Losec® MUPS Tablets 10 mg, 20 mg and 40 mg; Neon Healthcare Limited, The electronic Medicines Compendium. Dated March 2023.
Sobre el autorVer biografía completa

Michael Stewart, MRPharmS
Gerente de Revisión de Folletos de Medicamentos – Contratista, Farmacéutico
BPharm (Hons), MRPharmS
Michael es un farmacéutico comunitario que ejerce en Midlands y South Yorkshire con más de 20 años de experiencia asesorando sobre medicamentos y condiciones médicas. Tiene una sólida formación en capacitación en atención médica, habiendo producido e impartido cursos de formación para equipos de farmacia y personal de entornos de atención residencial, incluidas enfermeras. También ha contribuido a juntas asesoras de farmacia para la gestión de condiciones de baja gravedad en la comunidad.
Acerca del revisor

Sid Dajani
Sultan Dajani se graduó en la Escuela de Farmacia de Londres en 1994 y se convirtió en el miembro más joven elegido para el consejo de la Sociedad Real de Farmacia desde su fundación en 1842.
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Próxima revisión: 6 de agosto de 2026
7 Ago 2023 | Última versión

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