Olsalazine for ulcerative colitis
Revisado por Sid DajaniÚltima actualización por Michael Stewart, MRPharmSÚltima actualización 18 mar 2023
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Take olsalazine tablets or capsules with a meal or after a snack.
It is important that you keep your regular appointments with your doctor so that your progress can be checked. You will need to have regular blood tests.
Common side-effects tend to be minor, but on occasions, olsalazine can cause more serious problems. You should tell your doctor immediately if you have any unexplained bleeding, bruising, red or purple discolorations of your skin, a sore throat, a high temperature (fever) or you feel generally unwell.
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About olsalazine
Tipo de medicamento | Aminosalicylate |
Utilizado para | Ulcerative colitis in adults and in children aged over 12 years |
Disponible como | Capsules and tablets |
Ulcerative colitis causes inflammation of the large intestine. This can lead to damage to the lining of your intestine (ulceration) and bleeding, and causes symptoms of tummy (abdominal) pain and diarrhoea.
Although it is not clear exactly how olsalazine works, it is thought to act on the cells which line your intestine to change the way they make and release certain chemicals. These chemicals are thought to be a factor in causing the symptoms of ulcerative colitis. Olsalazine allows the damaged areas of your intestine to recover, and then helps to prevent your symptoms from flaring up again.
Before taking olsalazine
Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking olsalazine it is important that your doctor or pharmacist knows:
Si está embarazada, esperando un bebé o en período de lactancia.
Si tiene algún problema con el funcionamiento de sus riñones.
If you have asthma and/or experience severe allergies.
If you have ever had an allergic reaction to a medicine. It is particularly important that you tell your doctor if you have had an unusual reaction to aspirin or to any other salicylate medicine.
Si toma o utiliza otros medicamentos. Esto incluye cualquier medicamento que esté tomando y que pueda adquirirse sin receta, así como medicamentos a base de plantas y complementarios.
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How to take olsalazine
Before you start this treatment, read the manufacturer's printed information leaflet from inside your pack. The manufacturer's leaflet will give you more information about olsalazine and a full list of side-effects which you may experience from taking it.
Take olsalazine exactly as your doctor tells you to. He or she will tell you how many tablets/capsules to take for each dose, and when to take them.
Your dose may be increased over the first few weeks to make sure that you are taking a dose that best controls your symptoms.
Your dose may be reduced again once your symptoms have improved.
It is likely that you will be asked to take olsalazine twice each day, usually morning and evening. Some people may be asked to take it three times each day for a short while. The directions will be printed on the label of your pack to remind you.
Take olsalazine tablets or capsules with a drink of water during a meal, or straightaway after a meal. Taking olsalazine with or after food will help to keep side-effects, like diarrhoea, to a minimum.
If you forget to take a dose, take it as soon as you remember unless your next dose is due. If when you remember it is nearly time for your next dose, then leave out the forgotten dose but remember to take your next dose when it is due. Do not take two doses together to make up for a missed dose.
Aproveche al máximo su tratamiento
Try to keep your regular appointments with your doctor and clinic. This is so your doctor can check on your progress. Your doctor will want you to have regular blood tests during this treatment.
Treatment with olsalazine may be long-term in order to prevent your symptoms from flaring up from time to time. Continue to take it unless you are advised otherwise by your doctor.
Your doctor may advise you make some changes to your diet as part of your treatment. This may include a special diet or a nutritional supplement.
If you have an allergic condition, such as asthma, you should let your doctor know straightaway if you find your allergic symptoms get worse. If this happens, your doctor may want to review your treatment or will arrange to see you more often to keep an eye on your progress.
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Can olsalazine cause problems?
Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with olsalazine. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.
Common olsalazine side-effects - these affect fewer than 1 in 10 people who take this medicine | ¿Qué puedo hacer si me ocurre esto? |
Diarrea | Drink plenty of water to replace lost fluids. Make sure you take olsalazine after meals |
Feeling sick (nausea) or being sick (vomiting), indigestion, tummy (abdominal) pain | Coma alimentos sencillos: evite las comidas ricas o picantes. |
Headache, joint or muscle pain | Drink plenty of water and ask your pharmacist to recommend a suitable painkiller. If the pain continues, speak with your doctor |
Important: olsalazine can sometimes cause allergic reactions or problems with your blood cells. You should contact your doctor immediately if:
You have any difficulty in breathing, or any swelling of your face or tongue.
You have any unexplained bleeding, bruising, red or purple discolorations on your skin, a sore throat, a high temperature (fever), or if you feel generally unwell during this treatment.
Si experimenta cualquier otro síntoma que considere que puede deberse a este medicamento, consulte a su médico o farmacéutico.
How to store olsalazine
Mantenga todos los medicamentos fuera del alcance y de la vista de los niños.
Almacenar en un lugar fresco y seco, lejos del calor y la luz directos.
Información importante sobre todos los medicamentos
Información importante sobre todos los medicamentos
Si compra algún medicamento, compruebe con el farmacéutico que es seguro tomarlo con sus otros medicamentos.
No tome nunca más de la dosis prescrita. Si sospecha que usted u otra persona ha tomado una sobredosis de este medicamento, acuda al servicio de urgencias de su hospital. Llévese el envase, aunque esté vacío.
Si va a someterse a una operación o a un tratamiento dental, comunique a la persona que lleve a cabo el tratamiento qué medicamentos está tomando.
Este medicamento es para usted. Nunca se lo dé a otras personas aunque su enfermedad parezca ser la misma que la suya.
No guarde medicamentos caducados o que no desee. Llévelos a su farmacia local, que se encargará de eliminarlos por usted.
Si tiene cualquier duda sobre este medicamento pregunte a su farmacéutico.
Informar de los efectos secundarios de un medicamento o vacuna
Si experimenta efectos secundarios, puede notificarlos en línea a través del sitio web de la Tarjeta Amarilla.
Lecturas complementarias y referencias
- Manufacturer's PIL, Olsalazine sodium 250 mg Capsules; Atnahs Pharma UK Ltd, The electronic Medicines Compendium. Dated May 2021.
- Manufacturer's PIL, Olsalazine sodium 500 mg tablets; Atnahs Pharma UK Ltd, The electronic Medicines Compendium. Dated May 2021.
- Medicamentos BNF completa 89ª edición; Asociación Médica Británica y Real Sociedad Farmacéutica de Gran Bretaña, Londres.
Historia del artículo
La información de esta página ha sido redactada y revisada por médicos cualificados.
Fecha prevista para la próxima revisión: 17 mar 2026
18 mar 2023 | Última versión

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