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Comprimidos de medroxiprogesterona

Provera

Your dose of medroxyprogesterone will depend on what you are being treated for. Your doctor or pharmacist will tell you how many tablets to take and how often to take them.

Any side-effects are usually mild but can include feeling sick (nausea), irregular menstrual bleeding, weight gain and headache.


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About medroxyprogesterone

Tipo de medicamento

A progestogen (female hormone)

Utilizado para

Irregular or missed periods, endometriosis, and some cancers

También llamado

Provera®

Disponible como

Tabletas

Medroxyprogesterone belongs to a group of medicines called progestogens, which are female hormones.

When it is prescribed to help problems such as heavy, painful, irregular or missed periods, it works by replacing or supplementing the naturally produced female sex hormone called progesterone.

Medroxyprogesterone is also used for endometriosis. Endometriosis is a condition where tissue that normally lines the inside of your womb (uterus) is found elsewhere in your body, often in the pelvic area or tummy (abdomen). The cells in this tissue need oestrogen (another female sex hormone) to grow and survive. Medroxyprogesterone reduces the effect of oestrogen on these cells which causes them to 'shrink'. This means the patches of endometriosis also shrink.

Medroxyprogesterone is also prescribed (although at higher doses than in the conditions mentioned above) to help treat some cancers, particularly endometrial cancer.

Medroxyprogesterone is also available as an injection to prevent pregnancy, and as tablets (in combination with an oestrogen) for hormone replacement therapy (HRT) during the menopause. There are other medicine leaflets available which will give you more information about medroxyprogesterone when it is used for these reasons. See the separate leaflets called Medroxyprogesterone injection for contraception and Oestrogen and progestogen for HRT.

Before taking medroxyprogesterone

Some medicines are not suitable for people with certain conditions, and sometimes a medicine can only be used if extra care is taken. For these reasons, before you start taking medroxyprogesterone tablets, it is important that your doctor knows:

  • Si está embarazada o en periodo de lactancia.

  • Si tiene un problema en las arterias, llamado enfermedad arterial.

  • Si padece una enfermedad cardiaca.

  • If you have any of the following conditions: migraines, asthma, epilepsy, diabetes, or high blood pressure.

  • If you have any vaginal bleeding other than your normal monthly period.

  • Si alguna vez ha tenido un coágulo de sangre en las piernas o los pulmones.

  • If you have had any problems with the way your liver works, or if you have any problems with the way your kidneys work.

  • Si alguna vez has tenido depresión.

  • If you have ever had breast cancer, or a cancer that you have been told is dependent on a sex hormone (unless this is why you have been prescribed medroxyprogesterone).

  • Si padece un raro trastorno sanguíneo hereditario llamado porfiria.

  • Si alguna vez ha tenido una reacción alérgica a un medicamento.

  • Si toma o utiliza otros medicamentos. Esto incluye cualquier medicamento que esté tomando y que pueda adquirirse sin receta, así como medicamentos a base de plantas y complementarios.

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How to take medroxyprogesterone

  • Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack of tablets. It will give you more information about medroxyprogesterone and it will also provide you with a full list of the side-effects which you could experience from taking it.

  • Take medroxyprogesterone tablets exactly as your doctor tells you to. There are several strengths of tablets, so it is a good idea to make sure you have been given the same strength each time you collect a fresh supply. If you are unsure about this, ask your pharmacist to check the strength for you.

  • Your dose will depend on what you are being treated for. Your doctor will tell you how many tablets to take for each dose, and how often to take them. You may be asked to take the tablets every day, or only on certain days of your monthly cycle. The dose will also be printed on the label of the pack of tablets to remind you about what the doctor said to you but, if you are still unclear about how to take the tablets, you should ask your pharmacist to explain it to you again.

  • You can take medroxyprogesterone tablets either before or after meals. It is advisable to swallow the tablets with a drink of water.

  • Try to take your doses at the same time of day each day, as this will help you to remember to take medroxyprogesterone regularly. If you forget to take a dose, take it as soon as you remember (unless it is nearly time for your next dose, in which case leave out the missed dose and take the next dose as normal). Do not take two doses together to make up for a forgotten dose.

Aproveche al máximo su tratamiento

  • Intente acudir a las citas periódicas con su médico. Así podrá comprobar su evolución. No olvide tampoco acudir a las citas rutinarias para las pruebas de cribado mamario y las citologías cervicales.

  • These tablets are not for preventing pregnancy. If you need contraception you should discuss this with your doctor. It is important that you do not become pregnant whilst taking medroxyprogesterone as this treatment may harm your unborn baby.

  • If you have diabetes you may need to check your blood glucose more frequently, as the tablets can affect the levels of sugar in your blood. Your doctor will advise you about this.

  • It is best to avoid smoking and drinking too much alcohol while taking medroxyprogesterone. If you are a smoker and you would like advice on how to quit, speak with your doctor or pharmacist.

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Can medroxyprogesterone tablets cause problems?

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the ones associated with medroxyprogesterone tablets. You will find a full list in the manufacturer's information leaflet that has been given to you. The unwanted effects may improve as your body adjusts to the new medicine, but speak with your doctor, nurse or pharmacist if any of the following continue or become troublesome.

Medroxyprogesterone side-effects

¿Qué puedo hacer si me ocurre esto?

Dolor de cabeza

Ask your pharmacist to recommend a suitable painkiller. If the headache continues or is unusually severe, speak with your doctor as soon as possible

Sensación de malestar (náuseas)

Coma comidas sencillas (evite los alimentos ricos o picantes)

Irregular periods, breast tenderness, weight changes, feeling dizzy or tired, difficulty sleeping, changes in sexual desire, mood changes, skin rash, acne-like spots, changes in hair growth, swollen feet and ankles (due to fluid retention)

Hable con su médico si alguno de estos síntomas le resulta molesto

Si experimenta cualquier otro síntoma que crea que puede deberse a los comprimidos, hable con su médico o farmacéutico para que le aconsejen.

How to store medroxyprogesterone

  • Mantenga todos los medicamentos fuera del alcance y de la vista de los niños.

  • Almacenar en un lugar fresco y seco, lejos del calor y la luz directos.

Información importante sobre todos los medicamentos

Información importante sobre todos los medicamentos

No tome nunca más de la dosis prescrita. Si sospecha que usted u otra persona ha tomado una sobredosis de este medicamento, acuda inmediatamente al servicio de urgencias de su hospital. Llévese el envase, aunque esté vacío.

Este medicamento es para usted. Nunca se lo dé a otras personas aunque su enfermedad parezca ser la misma que la suya.

If you buy any medicines, always check with a pharmacist that they are suitable to take with your prescribed medicines.

If you are due to have an operation, please tell the person carrying out the treatment which medicines you are taking.

No guarde medicamentos caducados o que no desee. Llévelos a su farmacia local, que se encargará de eliminarlos por usted.

Si tiene cualquier duda sobre este medicamento pregunte a su farmacéutico.

Informar de los efectos secundarios de un medicamento o vacuna

Si experimenta efectos secundarios, puede notificarlos en línea a través del sitio web de la Tarjeta Amarilla.

Lecturas complementarias y referencias

Historia del artículo

La información de esta página ha sido redactada y revisada por médicos cualificados.

  • Fecha prevista para la próxima revisión: 3 mar 2028
  • 4 mar 2025 | Última versión

    Última actualización

    Michael Stewart, MRPharmS

    Revisado por expertos

    Sid Dajani
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