Granisetrón para las náuseas y los vómitos
Kytril, Sancuso
Revisado por pares por Sid DajaniÚltima actualización por Michael Stewart, MRPharmSÚltima actualización 9 Ene 2023
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Granisetron is an anti-sickness medicine for adults.
It is available as tablets to take by mouth, as a patch to be applied to the skin, and as an injection.
The most common side-effects are constipation and headache.
De un vistazo
Granisetron is an anti-sickness medicine (antiemetic) that prevents or treats nausea and vomiting.
It is used for sickness caused by chemotherapy, radiotherapy, or surgery.
You can take it as tablets, use a skin patch, or receive it by injection.
Possible side-effects include constipation and headache.
Seek medical help immediately if you develop stiff or shaky muscles, a very high temperature, a fast heartbeat, or become confused.
About granisetron
Tipo de medicamento | An anti-sickness medicine (antiemetic) - a serotonin (5HT3) receptor antagonist |
Usado para | Prevention or treatment of nausea and vomiting associated with quimioterapia, radioterapia or surgery (for adults) |
También llamado | Kytril®; Sancuso® |
Disponible como | Tablets, patches and injection |
Granisetron is an anti-sickness medicine, also known as an antiemetic. It is a serotonin receptor antagonist. It is prescribed to stop you from feeling sick (nauseated). It works by blocking the effect of a naturally produced chemical in your body, called serotonin. Serotonin is also referred to as 5HT3.
Chemotherapy, radiotherapy and surgery can all cause the release of an increased amount of serotonin in your body. There are tiny areas in your small intestine and brain, called 5HT3 receptors. Serotonin acts on these receptors and causes you to feel sick. Granisetron works by blocking serotonin from acting on the receptors, and this stops you from feeling sick or being sick (vomiting).
Before taking granisetron
Some medicines are not suitable for people with certain conditions, and sometimes a medicine can only be used if extra care is taken. For these reasons, before you start taking granisetron it is important that your doctor knows:
Si estás embarazada o amamantando.
If you have been told you have an irregular heartbeat.
Si tienes algún problema con el funcionamiento de tu hígado.
Si está tomando otros medicamentos. Esto incluye cualquier medicamento que esté tomando y que esté disponible para comprar sin receta, así como medicamentos herbales y complementarios.
Si alguna vez has tenido una reacción alérgica a un medicamento.
How to take granisetron
Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about granisetron, and it will also provide you with a full list of the side-effects which you could experience from taking it.
If you are being prescribed granisetron because you are due to have surgery, you will be given an injection of granisetron shortly before the operation. You could be given further doses by injection after the surgery if it is needed. A doctor or nurse will administer the injections to you.
If you are due to have a quimioterapia o radioterapia treatment that could cause you to feel sick, your doctor will prescribe granisetron for you to have before the treatment:
If you are able to take tablets, you will be given one dose of tablets to take within the hour before your treatment. You will then be asked to continue to take granisetron tablets for a few days - it is usual to be prescribed 2 mg daily (as one or two doses) for up to seven days. Swallow the tablets whole with a drink of water. You can take granisetron either with or without food.
If you are not able to take tablets, you could be given a skin patch containing granisetron. The patch will be applied to your upper arm, or possibly your tummy (abdomen), 24-48 hours before your treatment is due to begin. Leave it in place during your treatment and for a further 24 hours after the treatment has finished before you remove it. You can wash and bathe as normal while you are wearing the patch, but you should not allow the patch to be in direct contact with bright sunlight or heat (such as an electric blanket or a hot water bottle). Even after you have removed the patch, the area where the patch was should be protected from bright sunlight for a further 10 days. When you remove the patch, fold it in half with the sticky sides together, and ask your pharmacist or clinic to dispose of it.
Granisetron can also be given by injection. If this is the treatment prescribed for you, a doctor or nurse will administer the injections to you.
Obteniendo el máximo de tu tratamiento
Even if you do not feel like eating or drinking, try to sip water regularly to prevent you from becoming lacking in fluids (dehydrated). Also, rather than trying to eat three main meals a day, try eating small, simple but nourishing snacks, every few hours.
Can granisetron cause problems?
Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the more common ones associated with granisetron. The best place to find a full list of the side-effects which can be associated with your medicine, is from the manufacturer's printed information leaflet supplied with the medicine. Alternatively, you can find an example of a manufacturer's information leaflet in the reference section below. Speak with your doctor or pharmacist if any of the following continue or become troublesome.
Muy común granisetron side-effects (these affect more than 1 in 10 people) | ¿Qué puedo hacer si experimento esto? |
Estreñimiento | Try to eat a well-balanced diet, and drink several glasses of water each day. Let your doctor know if this continues |
Dolor de cabeza | Drink plenty of water and ask your doctor to prescribe a suitable painkiller |
Común granisetron side-effects (estos afectan a menos de 1 de cada 10 personas) | ¿Qué puedo hacer si experimento esto? |
Problemas para dormir | Esto debería pasar pronto |
Diarrea | Drink plenty of water, and if troublesome, speak with your doctor |
Cambios en algunos análisis de sangre | Su médico lo supervisará |
Importante: in a very few people, medicines like granisetron can cause a problem called serotonin syndrome. Although this occurs only rarely, should you develop stiff or shaky muscles, a very high temperature (fever), a fast heartbeat, or become confused or agitated, you should call for medical assistance straightaway.
Si experimenta otros síntomas que cree que pueden deberse al medicamento, hable con su médico o farmacéutico para obtener más consejos.
How to store granisetron
Mantenga todos los medicamentos fuera del alcance y la vista de los niños.
Almacenar en un lugar fresco y seco, lejos del calor y la luz directos.
Información importante sobre todos los medicamentos
Información importante sobre todos los medicamentos
Nunca tome más de la dosis prescrita. Si sospecha que usted u otra persona podría haber tomado una sobredosis de este medicamento, acuda al departamento de accidentes y emergencias de su hospital local. Lleve el envase con usted, incluso si está vacío.
Este medicamento es para ti. Nunca lo des a otras personas, incluso si su condición parece ser la misma que la tuya.
Si vas a someterte a una operación o a un tratamiento dental, informa a la persona que realiza el tratamiento sobre los medicamentos que estás tomando.
Si compras algún medicamento, consulta con un farmacéutico que sean adecuados para tomar con tus otros medicamentos.
No guardes medicamentos caducados o no deseados. Llévalos a tu farmacia local, que se encargará de desecharlos por ti.
Si tienes alguna pregunta sobre este medicamento, consulta a tu farmacéutico.
Informar efectos secundarios de un medicamento o vacuna
Si experimenta efectos secundarios, puede reportarlos en línea a través de Sitio web de Yellow Card.

¿Inseguro sobre mezclar medicamentos?
Verifica posibles interacciones entre medicamentos, suplementos y alimentos antes de tomarlos juntos.
Preguntas frecuentes
What should I do if I am prescribed granisetron and I am pregnant or breastfeeding?
If you are pregnant or breastfeeding, it's important to let your doctor know before you start taking granisetron. They will consider your specific situation and advise on the best course of action, as extra care may be needed.
Are there any conditions that would prevent me from taking granisetron?
Granisetron may not be suitable for everyone or might require extra caution. You should inform your doctor if you have an irregular heartbeat or any problems with your liver function before starting treatment.
Can I take other medicines, including over-the-counter or herbal remedies, with granisetron?
You should always tell your doctor about all medicines you are currently taking, including those bought without a prescription, as well as herbal and complementary medicines. This allows your doctor to check for any potential interactions before you start granisetron.
What should I do if I experience side-effects from granisetron that are not listed in the leaflet?
If you experience any symptoms that you believe might be related to taking granisetron, even if they are not listed in the manufacturer's leaflet, you should speak with your doctor or pharmacist for advice.
How should I dispose of used granisetron patches or any other unwanted granisetron medicine?
When you remove a granisetron patch, you should fold it in half so the sticky sides are together. For both used patches and any other out-of-date or unwanted granisetron medicine, you should take them to your local pharmacy for proper disposal.
Lecturas adicionales y referencias
- Manufacturer's PIL, Granisetron 1 mg film-coated tablets; Mylan, The electronic Medicines Compendium. Dated January 2021.
- Manufacturer's PIL, Sancuso® 3.1 mg/24 hours transdermal patch; Kyowa Kirin Ltd, The electronic Medicines Compendium. Dated April 2020.
- Medicamentos Completos BNF 89ª Edición; Asociación Médica Británica y Sociedad Real de Farmacia de Gran Bretaña, Londres.
Sobre el autorVer biografía completa

Michael Stewart, MRPharmS
Gerente de Revisión de Folletos de Medicamentos – Contratista, Farmacéutico
BPharm (Hons), MRPharmS
Michael es un farmacéutico comunitario que ejerce en Midlands y South Yorkshire con más de 20 años de experiencia asesorando sobre medicamentos y condiciones médicas. Tiene una sólida formación en capacitación en atención médica, habiendo producido e impartido cursos de formación para equipos de farmacia y personal de entornos de atención residencial, incluidas enfermeras. También ha contribuido a juntas asesoras de farmacia para la gestión de condiciones de baja gravedad en la comunidad.
Acerca del revisor

Sid Dajani
Sultan Dajani se graduó en la Escuela de Farmacia de Londres en 1994 y se convirtió en el miembro más joven elegido para el consejo de la Sociedad Real de Farmacia desde su fundación en 1842.
Historial del artículo
La información en esta página está escrita y revisada por pares por clínicos calificados.
Artículo también disponible en Inglés, Alemán, Español, Francés, Italiano, Portugués, Hindi, Hebreo, Árabe, y Sueco.
Próxima revisión: 8 Jul 2027
9 Ene 2023 | Última versión

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