Cotrimoxazol para la infección
Peer reviewed by Dr Colin Tidy, MRCGPLast updated by Michael Stewart, MRPharmSLast updated 19 Sept 2023
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Co-trimoxazole is a combination antibiotic. It can be taken by people who are allergic to penicillin, but it is not suitable for people who are allergic to sulfonamides.
Space out your doses evenly throughout the day, and remember to finish the course of treatment.
The most common side effects of co-trimoxazole are feeling sick (nausea), diarrhoea, and headache.
If you develop a skin rash or any allergic-type reaction, let your doctor know straightaway.
En este artículo:
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About co-trimoxazole
Tipo de medicamento | Un medicamento antibacteriano |
Utilizado para | To treat or prevent certain infections |
Disponible como | Tablet, oral liquid medicine and injection |
What is co-trimoxazole used for?
Co-trimoxazole is a type of antibiotic used to treat serious bacterial infections, particularly in people who have a problem with their immune system.
It is a combination of two antibacterial medicines - a sulfonamide medicine called sulfamethoxazole, and trimethoprim.
Although it has been prescribed widely for a range of infections in the past, it has very occasionally been associated with some serious side effects, and as a result is only now used for certain infections.
It works by killing the germs (bacteria) responsible for causing the infection.
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Side effects of co-trimoxazole
Common side effects of co-trimoxazole are:
Me siento mal.
Diarrea.
Dolor de cabeza.
Erupción cutánea.
Encontrará una lista completa en el prospecto del fabricante que acompaña al medicamento.
Los efectos no deseados suelen mejorar a medida que su organismo se adapta al nuevo medicamento, pero hable con su médico o farmacéutico si alguno de los siguientes continúa o se vuelve molesto.
How to manage co-trimoxazole side effects
Common co-trimoxazole side effects | ¿Qué puedo hacer si me ocurre esto? |
Feeling sick | Limítese a comidas sencillas: evite las comidas ricas o picantes |
Diarrea | Beber mucha agua para reponer los líquidos perdidos |
Dolor de cabeza | Bebe mucha agua y pide a tu farmacéutico que te recomiende un analgésico adecuado. Si los dolores de cabeza persisten, informe a su médico. |
Erupción cutánea | Contact your doctor for advice straightaway Do not take any more doses until you have spoken with a doctor |
Si experimenta cualquier otro síntoma que considere que puede deberse al medicamento, consulte a su médico o farmacéutico.
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Who should not take co-trimoxazole?
Some medicines aren’t suitable for certain health conditions or may require extra care. Before taking co-trimoxazole, it is important to let your doctor know:
Si está embarazada, esperando un bebé o en período de lactancia.
Si tiene algún problema con el funcionamiento del hígado o de los riñones.
Si tiene asma.
If you have a blood disorder. It is particularly important that you tell your doctor if you have a rare inherited blood disorder called porphyria.
If you have an enzyme deficiency called G6PD deficiency.
If you have been told you have low amounts of the vitamin folic acid.
Si está tomando otros medicamentos. Esto incluye cualquier medicamento que esté tomando y que pueda adquirirse sin receta, así como medicamentos a base de plantas y complementarios.
If you have ever had an allergic reaction to a medicine. It is particularly important that you tell your doctor if you have ever had a bad reaction to a sulfonamide antibiotic.
How to take co-trimoxazole
Read the information leaflet in the pack before you start. It explains the medicine and lists possible side effects.
Take co-trimoxazole exactly as your doctor tells you to. Your dose will depend upon whether you are being treated because you have an infection, or to prevent an infection.
It is usually taken twice a day, 12 hours apart for adults.
For children, it is usually a liquid medicine - the dose will depend on the age of your child.
Take co-trimoxazole regularly so that you keep a steady level of the medicine in your body.
Try to avoid missing any doses.
Co-trimoxazole is best taken with food or a drink.
If you miss a dose, take it as soon as you remember. If it’s nearly time for the next one, skip the missed dose. Do not take two doses at once.
Aproveche al máximo su tratamiento
Drink plenty of water each day while taking co-trimoxazole so you don’t get dehydrated.
Most people start to feel better after a few days. If you don’t improve, see your doctor as you may need a different antibiotic.
Keep taking the medicine until you finish the full course, even if you feel better, unless your doctor tells you to stop. This helps stop the infection from coming back.
Some people get thrush (oral or vaginal) after antibiotics. If this happens, ask your doctor or pharmacist for advice.
Si va a someterse a una operación o a un tratamiento dental, comunique a la persona que lleve a cabo el tratamiento qué medicamentos está tomando.
If you buy any medicines, check with a pharmacist that they are suitable to take with co-trimoxazole.
This medicine can stop the oral typhoid vaccine from working. Tell your healthcare provider you’re taking it if you’re due for any vaccines.
Si sigue sintiéndose mal después de tomar el antibiótico, pida otra cita con su médico.
How to store co-trimoxazole
Mantenga todos los medicamentos fuera del alcance y de la vista de los niños.
Almacenar en un lugar fresco y seco, lejos del calor y la luz directos.
Información importante sobre todos los medicamentos
Información importante sobre todos los medicamentos
No tome nunca más de la dosis prescrita. Si sospecha que usted u otra persona ha tomado una sobredosis de este medicamento, acuda al servicio de urgencias de su hospital. Llévese el envase, aunque esté vacío.
Este medicamento es para usted. Nunca se lo dé a otras personas aunque su enfermedad parezca ser la misma que la suya.
No guarde medicamentos caducados o que no desee. Llévelos a su farmacia local, que se encargará de eliminarlos por usted.
Si tiene cualquier duda sobre este medicamento pregunte a su farmacéutico.
Informar de los efectos secundarios de un medicamento o vacuna
Si experimenta efectos secundarios, puede notificarlos en línea a través del sitio web de la Tarjeta Amarilla.
Preguntas más frecuentes
How long does it take for co-trimoxazole take to work?
Co-trimoxazole usually starts working within 1-3 days. Most people start to notice an improvement in their symptoms within a few days of taking the first dose. Always finish the full course of treatment even if you are feeling better.
Is co-trimoxazole safe to take during pregnancy?
Co-trimoxazole is not usually recommended to take during pregnancy, especially in the first and third trimesters. Always let your doctor know if you are pregnant or are planning on becoming pregnant before taking co-trimoxazole.
Can you drink alcohol while taking co-trimoxazole?
Drinking alcohol while taking co-trimoxazole can worsen side effects such as nausea, dizziness, and stomach upset. It is best to avoid alcohol until you have finished your course of treatment, however, moderate consumption is generally considered to be safe.
How long does co-trimoxazole stay in your system for?
Co-trimoxazole stays in your system for 2-3 days after your last dose, however, it may last longer for people with kidney problems.
Lecturas complementarias y referencias
- Manufacturer's PIL, Co-Trimoxazole Tablets 80/400 mg; Aspen, The electronic Medicines Compendium. Dated July 2021.
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Historia del artículo
La información de esta página ha sido redactada y revisada por médicos cualificados.
Próxima revisión prevista: 18 de septiembre 2026
19 Sept 2023 | Última versión

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