Co-trimoxazole for infection
Revisado por pares por Dr Colin Tidy, MRCGPÚltima actualización por Michael Stewart, MRPharmSLast updated 19 Sept 2023
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Co-trimoxazole is a combination antibiotic. It can be taken by people who are allergic to penicillin, but it is reportado suitable for people who are allergic to sulfonamides.
Space out your doses evenly throughout the day, and remember to finish the course of treatment.
The most common side effects of co-trimoxazole are feeling sick (nausea), diarrhoea, and headache.
If you develop a skin rash or any allergic-type reaction, let your doctor know de inmediato.
En este artículo:
Video picks for Medicamentos para el tratamiento de infecciones
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About co-trimoxazole
Tipo de medicamento | An antibacterial medicine |
Usado para | To treat or prevent certain infections |
Disponible como | Tablet, oral liquid medicine and injection |
What is co-trimoxazole used for?
Volver al contenidoCo-trimoxazole is a type of antibiótico used to treat serious bacterial infections, particularly in people who have a problem with their immune system.
It is a combination of two antibacterial medicines - a sulfonamide medicine called sulfamethoxazole, and trimetoprima.
Although it has been prescribed widely for a range of infections in the past, it has very occasionally been associated with some serious side effects, and as a result is only now used for certain infections.
It works by killing the germs (bacteria) responsible for causing the infection.
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Side effects of co-trimoxazole
Volver al contenidoCommon side effects of co-trimoxazole are:
Náuseas.
Diarrea.
Dolor de cabeza.
Erupción cutánea.
You will find a full list in the manufacturer's information leaflet supplied with your medicine.
Los efectos no deseados a menudo mejoran a medida que su cuerpo se adapta al nuevo medicamento, pero hable con su médico o farmacéutico si alguno de los siguientes persiste o se vuelve problemático.
How to manage co-trimoxazole side effects
Volver al contenidoCommon co-trimoxazole side effects | ¿Qué puedo hacer si experimento esto? |
Feeling sick | Stick to simple foods - avoid rich or spicy foods |
Diarrea | Bebe mucha agua para reponer los líquidos perdidos |
Dolor de cabeza | Bebe mucha agua y pide a tu farmacéutico que te recomiende un analgésico adecuado. Si los dolores de cabeza continúan, informa a tu médico |
Erupción cutánea | Contacta a tu médico para recibir asesoramiento de inmediato Do not take any more doses until you have spoken with a doctor |
Si experimenta otros síntomas que cree que pueden deberse al medicamento, hable con su médico o farmacéutico para obtener más consejos.
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Who should not take co-trimoxazole?
Volver al contenidoSome medicines aren’t suitable for certain health conditions or may require extra care. Before taking co-trimoxazole, it is important to let your doctor know:
Si estás embarazada, intentando concebir o amamantando.
Si tiene algún problema con el funcionamiento de su hígado o de sus riñones.
Si tienes asma.
If you have a blood disorder. It is particularly important that you tell your doctor if you have a rare inherited blood disorder called porphyria.
If you have an enzyme deficiency called G6PD deficiency.
If you have been told you have low amounts of the vitamin folic acid.
Si está tomando otros medicamentos. Esto incluye cualquier medicamento que esté tomando y que esté disponible para comprar sin receta, así como medicamentos herbales y complementarios.
If you have ever had an allergic reaction to a medicine. It is particularly important that you tell your doctor if you have ever had a bad reaction to a sulfonamide antibiotic.
How to take co-trimoxazole
Volver al contenidoRead the information leaflet in the pack before you start. It explains the medicine and lists possible side effects.
Take co-trimoxazole exactly as your doctor tells you to. Your dose will depend upon whether you are being treated because you have an infection, or to prevent an infection.
It is usually taken twice a day, 12 hours apart for adults.
For children, it is usually a liquid medicine - the dose will depend on the age of your child.
Take co-trimoxazole regularly so that you keep a steady level of the medicine in your body.
Try to avoid missing any doses.
Co-trimoxazole is best taken with food or a drink.
If you miss a dose, take it as soon as you remember. If it’s nearly time for the next one, skip the missed dose. Do not take two doses at once.
Obteniendo el máximo de tu tratamiento
Volver al contenidoDrink plenty of water each day while taking co-trimoxazole so you don’t get dehydrated.
Most people start to feel better after a few days. If you don’t improve, see your doctor as you may need a different antibiotic.
Keep taking the medicine until you finish the full course, even if you feel better, unless your doctor tells you to stop. This helps stop the infection from coming back.
Some people get thrush (oral o vaginal) after antibiotics. If this happens, ask your doctor or pharmacist for advice.
Si vas a someterte a una operación o tratamiento dental, informa a la persona que realiza el tratamiento sobre los medicamentos que estás tomando.
If you buy any medicines, check with a pharmacist that they are suitable to take with co-trimoxazole.
This medicine can stop the oral vacuna oral contra la fiebre tifoidea from working. Tell your healthcare provider you’re taking it if you’re due for any vaccines.
Si aún te sientes mal después de completar tu tratamiento con el antibiótico, programa otra cita para ver a tu médico.
How to store co-trimoxazole
Volver al contenidoMantenga todos los medicamentos fuera del alcance y la vista de los niños.
Almacenar en un lugar fresco y seco, lejos del calor y la luz directos.
Información importante sobre todos los medicamentos
Volver al contenidoInformación importante sobre todos los medicamentos
Nunca tome más de la dosis prescrita. Si sospecha que usted u otra persona podría haber tomado una sobredosis de este medicamento, acuda al departamento de accidentes y emergencias de su hospital local. Lleve el envase con usted, incluso si está vacío.
Este medicamento es para ti. Nunca lo des a otras personas, incluso si su condición parece ser la misma que la tuya.
No guardes medicamentos caducados o no deseados. Llévalos a tu farmacia local, que se encargará de desecharlos por ti.
Si tienes alguna pregunta sobre este medicamento, consulta a tu farmacéutico.
Informar efectos secundarios de un medicamento o vacuna
Si experimenta efectos secundarios, puede reportarlos en línea a través de Yellow Card website.
Preguntas frecuentes
Volver al contenidoHow long does it take for co-trimoxazole take to work?
Co-trimoxazole usually starts working within 1-3 days. Most people start to notice an improvement in their symptoms within a few days of taking the first dose. Always finish the full course of treatment even if you are feeling better.
Is co-trimoxazole safe to take during pregnancy?
Co-trimoxazole is not usually recommended to take during pregnancy, especially in the first and third trimesters. Always let your doctor know if you are pregnant or are planning on becoming pregnant before taking co-trimoxazole.
Can you drink alcohol while taking co-trimoxazole?
Drinking alcohol while taking co-trimoxazole can worsen side effects such as nausea, dizziness, and stomach upset. It is best to avoid alcohol until you have finished your course of treatment, however, moderate consumption is generally considered to be safe.
How long does co-trimoxazole stay in your system for?
Co-trimoxazole stays in your system for 2-3 days after your last dose, however, it may last longer for people with kidney problems.

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Verifica posibles interacciones entre medicamentos, suplementos y alimentos antes de tomarlos juntos.
Lecturas adicionales y referencias
- Manufacturer's PIL, Co-Trimoxazole Tablets 80/400 mg; Aspen, The electronic Medicines Compendium. Dated July 2021.
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Historial del artículo
La información en esta página está escrita y revisada por pares por clínicos calificados.
Próxima revisión: 18 de septiembre de 2026
19 Sept 2023 | Última versión

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