Cotrimoxazol para la infección
Revisado por Sid DajaniÚltima actualización por Michael Stewart, MRPharmSÚltima actualización 19 Sept 2023
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Co-trimoxazole is a combination antibiotic. It can be taken by people who are allergic to penicillin, but it is not suitable for people who are allergic to sulfonamides.
Space out your doses evenly throughout the day, and remember to finish the course of treatment.
The most common side-effects are feeling sick, diarrhoea and headache. If you develop a skin rash or any allergic-type reaction, let your doctor know straightaway.
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About co-trimoxazole
Tipo de medicamento | Un medicamento antibacteriano |
Utilizado para | To treat or prevent certain infections |
Disponible como | Tablet, oral liquid medicine and injection |
Co-trimoxazole is a combination of two antibacterial medicines - a sulfonamide medicine called sulfamethoxazole, and trimethoprim. Although it has been prescribed widely for a range of infections in the past, it has very occasionally been associated with some serious side-effects. As a result, other antibiotics are now preferred to treat simple infections and co-trimoxazole is usually reserved for the treatment of more serious infections. In particular, it is prescribed for infections which can occur in people who have a problem with their immune systems. It works by killing the germs (bacteria) responsible for causing the infection.
Before taking co-trimoxazole
Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking co-trimoxazole it is important that your doctor knows:
Si está embarazada, esperando un bebé o en período de lactancia.
Si tiene algún problema con el funcionamiento del hígado o de los riñones.
Si tiene asma.
If you have a blood disorder. It is particularly important that you tell your doctor if you have a rare inherited blood disorder called porphyria.
If you have an enzyme deficiency called G6PD deficiency.
If you have been told you have low amounts of the vitamin folic acid.
Si está tomando otros medicamentos. Esto incluye cualquier medicamento que esté tomando y que pueda adquirirse sin receta, así como medicamentos a base de plantas y complementarios.
If you have ever had an allergic reaction to a medicine. It is particularly important that you tell your doctor if you have ever had a bad reaction to a sulfonamide antibiotic.
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How to take co-trimoxazole
Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about co-trimoxazole and will provide you with a full list of the side-effects which you may experience from taking it.
Take co-trimoxazole exactly as your doctor tells you to. Your dose will depend upon whether you are being treated because you have an infection, or to prevent an infection. As a guide, it is usual to take two doses of co-trimoxazole daily (12 hours apart) to treat an infection, but make sure you read the directions on the label, as your dose may be different to this. If co-trimoxazole has been prescribed for your child, it is likely that you will be supplied a liquid medicine - the dose will depend upon the age of the child. Read the directions on the label carefully and make sure you measure out the correct dose.
Remember to take co-trimoxazole regularly so that you keep a steady level of the medicine in your body. Try to avoid missing any doses.
Co-trimoxazole is best taken with food or a drink.
If you forget to take a dose, take it as soon as you remember. If it is almost time to take your next dose when you remember, skip the missed dose and take your next dose when it is due. Do not take two doses together to make up for a forgotten dose.
Aproveche al máximo su tratamiento
Try to drink several glasses of water each day while you are on co-trimoxazole. It is important that you do not become lacking in fluid in the body (dehydrated).
Most people improve within a few days of starting treatment. If your symptoms do not improve despite taking co-trimoxazole, go back to see your doctor, as you may need an alternative antibiotic. This is because some bacteria are resistant to some types of antibiotics.
Even if you feel your infection has cleared up, keep taking the antibiotic until the course is finished (unless your doctor tells you otherwise). This is to prevent the infection from coming back and being more difficult to treat. A typical course of treatment will last for 5-7 days, although the treatment of some of the more serious infections can take longer than this.
Some people develop thrush (a yeast infection which causes redness and itchiness in the mouth or vagina) after taking a course of antibiotics. If you think you have thrush speak to your doctor or pharmacist for advice.
Si va a someterse a una operación o a un tratamiento dental, comunique a la persona que lleve a cabo el tratamiento qué medicamentos está tomando.
If you buy any medicines, check with a pharmacist that they are suitable to take with co-trimoxazole.
This medicine may stop the oral typhoid vaccine from working. If you are due to have any vaccinations, make sure the person treating you knows that you are taking it.
Si sigue sintiéndose mal después de tomar el antibiótico, pida otra cita con su médico.
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Can co-trimoxazole cause problems?
Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with co-trimoxazole. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.
Común co-trimoxazole side-effects | ¿Qué puedo hacer si me ocurre esto? |
Sensación de malestar (náuseas) | Limítese a comidas sencillas: evite las comidas ricas o picantes |
Diarrea | Beber mucha agua para reponer los líquidos perdidos |
Dolor de cabeza | Bebe mucha agua y pide a tu farmacéutico que te recomiende un analgésico adecuado. Si los dolores de cabeza persisten, informe a su médico. |
Erupción cutánea | Contact your doctor for advice directamente . Do not take any more doses until you have spoken with a doctor |
Si experimenta cualquier otro síntoma que considere que puede deberse al medicamento, consulte a su médico o farmacéutico.
How to store co-trimoxazole
Mantenga todos los medicamentos fuera del alcance y de la vista de los niños.
Almacenar en un lugar fresco y seco, lejos del calor y la luz directos.
Información importante sobre todos los medicamentos
Información importante sobre todos los medicamentos
No tome nunca más de la dosis prescrita. Si sospecha que usted u otra persona ha tomado una sobredosis de este medicamento, acuda al servicio de urgencias de su hospital. Llévese el envase, aunque esté vacío.
Este medicamento es para usted. Nunca se lo dé a otras personas aunque su enfermedad parezca ser la misma que la suya.
No guarde medicamentos caducados o que no desee. Llévelos a su farmacia local, que se encargará de eliminarlos por usted.
Si tiene cualquier duda sobre este medicamento pregunte a su farmacéutico.
Informar de los efectos secundarios de un medicamento o vacuna
Si experimenta efectos secundarios, puede notificarlos en línea a través del sitio web de la Tarjeta Amarilla.
Lecturas complementarias y referencias
- Manufacturer's PIL, Co-Trimoxazole Tablets 80/400 mg; Aspen, The electronic Medicines Compendium. Dated July 2021.
- Medicamentos BNF completa 89ª edición; Asociación Médica Británica y Real Sociedad Farmacéutica de Gran Bretaña, Londres.
Historia del artículo
La información de esta página ha sido redactada y revisada por médicos cualificados.
Fecha de la próxima revisión: 18 de septiembre de 2026
19 Sept 2023 | Última versión

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