Ungüento de calcitriol para la psoriasis
Silkis
Revisado por pares por Sid DajaniÚltima actualización por Michael Stewart, MRPharmSÚltima actualización 19 Nov 2024
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Apply a thin layer of ointment twice a day, morning and evening.
Do not use more than the maximum recommended amount of ointment each day.
Remember to wash your hands well after using calcitriol. This will help to prevent accidentally getting it on other areas of your skin, which could cause irritation.
Calcitriol can cause skin irritation. If this becomes severe, stop using the ointment and ask your doctor or pharmacist for further advice.
De un vistazo
Calcitriol ointment treats plaque psoriasis in adults and children over 12 years old.
It helps by slowing down the overproduction of skin cells.
You should apply a thin layer twice a day to affected areas.
Do not use more than 30g daily or on more than one-third of your body.
Common side-effects include skin redness, itching, and irritation.
You should see an improvement in your skin within a few weeks.
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About calcitriol
Tipo de medicamento | A topical vitamin D analogue |
Usado para | Plaque psoriasis in adults and in children aged over 12 years |
También llamado | Silkis® |
Disponible como | Ungüento |
Calcitriol is used to treat psoriasis en placas - this is the most common type of psoriasis. It is a condition where red scaly patches called plaques develop on your skin. The most common areas affected are over your elbows and knees, the scalp, and the lower part of your back. The patches may vary in size from time to time and can be itchy. Treatment for psoriasis aims to clear the plaques as much as possible.
Psoriasis is caused by cells in the outer layer of your skin multiplying faster than normal. This causes the older and dead skin cells to build up on the surface of your skin, causing the red scaly patches. Calcitriol works by slowing this overproduction of skin cells which eases the inflamed, scaly areas. It is similar to vitamin D, which is a vitamin essential for healthy skin.
Calcitriol can be taken orally as capsules to treat certain bone problems. Information on this use can be found in our separate medicine leaflet Capsulas de calcitriol.
Before using calcitriol
Volver al contenidoTo make sure that this is the right treatment for you, before you start using calcitriol ointment it is important that your doctor knows:
Si estás embarazada, intentando tener un bebé o amamantando.
If you have been told you have a form of psoriasis known as erythrodermic or pustular psoriasis. This is because more severe forms of psoriasis like these should only be treated with the close supervision from a skin specialist doctor.
If you have been told you have high calcium levels in your blood, or if your body has problems processing calcium.
Si tienes algún problema con el funcionamiento de tus riñones, o algún problema con el funcionamiento de tu hígado.
If you are taking any other medicines or using any other skin preparations. This includes any medicines which are available to buy without a prescription, as well as herbal and complementary medicines.
Si alguna vez has tenido una reacción alérgica a un medicamento.
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How to use calcitriol
Volver al contenidoBefore you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about applying calcitriol and will provide you with a full list of the side-effects which you could experience from using it.
Wash and dry the areas of your skin which are affected and then apply a thin layer of ointment. Do this twice each day - it is usually recommended that you apply calcitriol in the morning, and in the evening before going to bed.
You should not use more than 30 g of calcitriol ointment per day, and you should not apply it to more than a third of your body surface area each day. As a guide, a third of your body is approximately one full arm and one full leg. This is because calcitriol is absorbed through your skin and can cause problems if more than these amounts are used.
Wash your hands well afterwards. This will help to prevent the ointment from getting on to any areas of your skin which are unaffected by psoriasis, and causing irritation.
Obteniendo el máximo de tu tratamiento
Volver al contenidoIntenta mantener tus citas regulares con tu médico. Esto es para que tu médico pueda verificar tu progreso.
If you are also using a moisturiser for your skin, use this first and then wait until it has soaked into your skin before you apply calcitriol ointment.
Do not cover any areas of skin that have been treated with calcitriol with a dressing or a bandage. This is because it would cause you to absorb too much calcium into your bloodstream and this will cause problems.
If you have been advised to use calcitriol on your face, apply it carefully so that you do not get any ointment into your eyes. Also, remember to apply a thin layer only, as there is a greater chance it could cause irritation on your face.
You should start to see an improvement in your skin within a few weeks. This improvement will continue for a further few weeks until you feel the full benefit. Continue to apply the ointment regularly for as long as you have been recommended so that you get the full benefit.
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Can calcitriol cause problems?
Volver al contenidoAlong with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with calcitriol. You will find a full list in the manufacturer's information leaflet supplied with the medicine. The unwanted effects often improve as your body adjusts to the new medicine but speak with your doctor or pharmacist if any of the following continue or become troublesome.
Common calcitriol side-effects (these affect fewer than 1 in 10 people) | ¿Qué puedo hacer si experimento esto? |
Skin redness, itching, discomfort or irritation | This is usually mild, but if it continues or becomes severe, please speak with your doctor as it may be a sign of an allergic reaction |
Importante: there is a risk of fire when creams and ointments are absorbed by fabrics (such as clothing or bedsheets), making them flammable. A spark or flame can easily ignite the fabric. The risk is highest when large amounts of paraffin-based products are applied and absorb into fabrics. However, there is also a risk when non-paraffin products are used. Be aware of this fire hazard when repeatedly using large amounts of any skin product. Do not smoke or go near naked flames.
Cuando se use según las indicaciones de su médico o farmacéutico, este producto se aplicará en pequeñas cantidades en áreas pequeñas de la piel. Debería haber una absorción mínima en las telas y un menor riesgo de incendio.
If you experience any other symptoms which you think may be due to the ointment, please speak with your doctor or pharmacist for further advice.
How to store calcitriol
Volver al contenidoMantenga todos los medicamentos fuera del alcance y la vista de los niños.
Almacenar en un lugar fresco y seco, lejos del calor y la luz directos.
Calcitriol ointment only keeps for eight weeks once the tube has been opened, so do not use any ointment from a tube which has been opened for longer than this. Request a fresh supply through your doctor.
Información importante sobre todos los medicamentos
Volver al contenidoInformación importante sobre todos los medicamentos
Si compras algún medicamento, consulta con un farmacéutico que sea seguro tomarlo junto con tus otros medicamentos.
Si va a someterse a una operación o tratamiento dental, por favor informe a la persona que realiza el tratamiento qué medicamentos está tomando o usando.
Esta preparación es solo para uso en la piel. Si alguien ingiere algo de esto por accidente, acuda al departamento de accidentes y emergencias de su hospital local. Lleve el envase con usted, incluso si está vacío.
Este medicamento es para ti. Nunca lo des a otras personas, incluso si su condición parece ser la misma que la tuya.
No guardes medicamentos caducados o no deseados. Llévalos a tu farmacia local, que se encargará de desecharlos por ti.
Si tienes alguna pregunta sobre este medicamento, consulta a tu farmacéutico.
Informar efectos secundarios de un medicamento o vacuna
Si experimenta efectos secundarios, puede reportarlos en línea a través de Sitio web de Yellow Card.

¿Inseguro sobre mezclar medicamentos?
Verifica posibles interacciones entre medicamentos, suplementos y alimentos antes de tomarlos juntos.
Preguntas frecuentes
Can calcitriol ointment be used to treat other types of psoriasis?
Calcitriol ointment is specifically used to treat plaque psoriasis, which is the most common type. If you have more severe forms of psoriasis, such as erythrodermic or pustular psoriasis, these should only be treated under the close supervision of a skin specialist doctor, and calcitriol ointment may not be suitable.
How does calcitriol work to improve my psoriasis?
Psoriasis occurs because skin cells multiply too quickly, leading to scaly patches. Calcitriol, a substance similar to vitamin D which is essential for healthy skin, works by slowing down this overproduction of skin cells. This action helps to reduce the inflammation and scaliness of the affected areas of your skin.
Are there any specific situations where I should be careful about using calcitriol, even if it's for plaque psoriasis?
Yes, there are some important considerations. You should inform your doctor if you have high calcium levels in your blood, have problems processing calcium, or have kidney or liver problems. Additionally, if you are pregnant, trying to conceive, or breastfeeding, your doctor needs to be aware before you start using calcitriol.
What should I do if I accidentally get calcitriol ointment in my eyes?
The article advises applying calcitriol carefully to your face to avoid getting it into your eyes. If it does get into your eyes, the article does not provide specific instructions. However, it states that the preparation is for use on the skin only and if someone swallows some, they should go to accident and emergency. It's always best to contact a healthcare professional for advice on accidental exposure to sensitive areas.
How long will it take to see an improvement in my skin after starting calcitriol?
You should generally start to notice an improvement in your skin within a few weeks of beginning treatment. This improvement will continue over the next few weeks until you experience the full benefits. It's important to continue applying the ointment regularly as recommended by your doctor to achieve and maintain the best results.
Can I use calcitriol at the same time as my regular moisturiser?
Yes, you can use a moisturiser. If you are also using a moisturiser for your skin, you should apply it first. Then, wait until the moisturiser has fully soaked into your skin before you apply the calcitriol ointment.
What is the shelf-life of calcitriol ointment once I open the tube?
Once a tube of calcitriol ointment has been opened, it only remains effective for eight weeks. After this period, you should not use any remaining ointment from that tube. You will need to request a fresh supply from your doctor.
Is there a fire risk associated with calcitriol ointment like with some other skin creams?
Although the fire risk is highest with paraffin-based products, there is also a risk when non-paraffin products are used if absorbed by fabrics. When calcitriol is used as directed in small quantities, there should be minimal absorption into fabrics and a lower risk of fire. However, you should still be aware of this hazard and avoid smoking or going near naked flames when using any skin product.
Lecturas adicionales y referencias
- Manufacturer's PIL, Silkis® 3 micrograms per gram ointment; Galderma (U.K) Ltd, The electronic Medicines Compendium. Dated May 2024.
- Medicamentos Completos BNF 89ª Edición; Asociación Médica Británica y Sociedad Real de Farmacia de Gran Bretaña, Londres.
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Sobre el autorVer biografía completa

Michael Stewart, MRPharmS
Gerente de Revisión de Folletos de Medicamentos – Contratista, Farmacéutico
BPharm (Hons), MRPharmS
Michael es un farmacéutico comunitario que ejerce en Midlands y South Yorkshire con más de 20 años de experiencia asesorando sobre medicamentos y condiciones médicas. Tiene una sólida formación en capacitación en atención médica, habiendo producido e impartido cursos de formación para equipos de farmacia y personal de entornos de atención residencial, incluidas enfermeras. También ha contribuido a juntas asesoras de farmacia para la gestión de condiciones de baja gravedad en la comunidad.
Acerca del revisor

Sid Dajani
Sultan Dajani se graduó en la Escuela de Farmacia de Londres en 1994 y se convirtió en el miembro más joven elegido para el consejo de la Sociedad Real de Farmacia desde su fundación en 1842.
Historial del artículo
La información en esta página está escrita y revisada por pares por clínicos calificados.
Próxima revisión: 25 Nov 2027
19 Nov 2024 | Última versión

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