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Tabletas de bupropión para ayudar a dejar de fumar

Zyban

A combination of bupropion with counselling can increase your chance of successfully stopping smoking.

Comienza a tomar las tabletas al menos una semana antes de la fecha en que planeas dejar de fumar.

The most common side-effect is difficulty sleeping - the risk of this is less if you avoid taking doses near bedtime.

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About bupropion

Tipo de medicamento

A smoking cessation aid

Usado para

Ayudando a las personas a dejar de fumar

También llamado

Zyban®

Disponible como

Tabletas

Nicotine is a drug that is inhaled from the tobacco in cigarettes. It gets into the bloodstream, and stimulates the brain. Most regular smokers are addicted to nicotine. Even though you want to quit smoking, puede ser difícil tener éxito, porque la adicción a la nicotina es fuerte y difícil de romper. This is where bupropion can help.

Stopping smoking in somebody who smokes regularly causes a reduction of some chemicals in the brain. This leads to withdrawal symptoms such as cravings, anxiety, irritability and other symptoms associated with 'giving up'. Bupropion alters the levels of some of these chemicals and this is possibly how it relieves the withdrawal symptoms.

Bupropion does not 'make' you stop smoking. You still need determination to succeed and to break the smoking habit. A combination of bupropion with counselling from a nurse, doctor, pharmacist, or other health professional increases your chance of successfully stopping smoking. Therefore, most doctors will only prescribe bupropion to people who really want to stop smoking as part of a 'stopping smoking' programme.

Bupropion is also available as a combination product to support weight loss. If you are taking bupropion for this purpose and you need additional information, ask your pharmacist or doctor for advice.

Before taking bupropion

Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking bupropion it is important that your doctor knows:

  • If you are under 18 years of age, or over 65 years old.

  • Si estás embarazada o amamantando.

  • Si tienes algún problema con el funcionamiento de tu hígado, o algún problema con el funcionamiento de tus riñones.

  • Si tienes diabetes (diabetes mellitus).

  • Si por alguna razón estás en riesgo de tener una convulsión.

  • If you have ever had an eating disorder, such as anorexia nervosa or bulimia.

  • If you have bipolar disorder.

  • Si tienes una condición inflamatoria llamada lupus eritematoso sistémico (también conocido como lupus o LES).

  • If you regularly drink a lot of alcohol or if you have a drug problem.

  • If you have been told you have a tumour of the brain or spinal cord, or if you have ever had a serious head injury.

  • If you are taking any other medicines. This includes any medicines you are taking which are available to buy without a prescription, as well as herbal and complementary medicines. This is particularly important if you are taking digoxin for a heart condition. Your dose of digoxin may need to be adjusted before or after treatment with bupropion.

  • Si alguna vez has tenido una reacción alérgica a un medicamento.

How to take bupropion

  • Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about bupropion and stopping smoking. It will also provide you with a full list of the side-effects which can be associated with bupropion.

  • Take bupropion exactly as your doctor tells you to. You will be asked to set yourself a date on which to stop smoking. Your doctor will then ask you to start taking bupropion tablets at least a week before this 'quit' date. The aim is to build up the dose so that your body gets used to the medicine before your quit date.

  • Start by taking one tablet (150 mg) each day for the first six days. Then from day seven onwards, take one tablet twice a day (unless you are told otherwise by your doctor). Make sure that you leave at least eight hours between the doses. Ideally, take one tablet in the morning and one early evening. Remember to stop smoking on the day you have set as your quit date.

  • It is not important whether you take bupropion tablets before or after food, but it is best if you try to take your doses at the same time(s) each day. This will help you to remember to take the tablets regularly.

  • Swallow the tablets whole with a glass of water - do not chew or break the tablets before you swallow.

  • If you forget to take a dose, leave out the missed dose but make sure that you remember to take your next dose when it is due. Do not take two doses together to make up for the forgotten dose.

Obteniendo el máximo de tu tratamiento

  • Try to keep your regular appointments with your doctor or nurse. This is so that you can be given counselling and encouragement, and also so that a check can be kept on your progress. You will also need to have your blood pressure measured regularly, as this can increase in some people.

  • Asegúrese de que su médico o profesional de la salud sepa si está tomando otros medicamentos. Esto se debe a que dejar de fumar puede cambiar la forma en que su cuerpo descompone ciertos medicamentos. Por lo tanto, como resultado de dejar de fumar, es posible que sea necesario ajustar la dosis de algunos medicamentos recetados.

  • A full course of treatment with bupropion will last for 7-9 weeks in total. If you are still smoking after seven weeks, let your doctor know about this so that you can discuss the options that are available to you.

  • After your course of treatment, your doctor may suggest that you gradually reduce the dose over a few days before you finally stop taking the tablets.

  • Si compras algún medicamento, siempre consulta con un farmacéutico que sea seguro tomarlos junto con tus otros medicamentos.

Can bupropion cause problems?

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with bupropion. You will find a full list in the manufacturer's information leaflet supplied with your medicine. Some of the symptoms may also occur as a result of stopping smoking.

Common bupropion side-effects

¿Qué puedo hacer si experimento esto?

Dificultad para dormir

Intenta evitar tomar tu última dosis cerca de la hora de dormir

Feeling dizzy, difficulty concentrating

Si esto ocurre, no conduzca y no use herramientas o máquinas hasta que se sienta mejor

Dolor de cabeza

Bebe mucha agua y pide a tu farmacéutico que te recomiende un analgésico adecuado. Si los dolores de cabeza continúan, informa a tu médico

Boca seca

Intenta masticar chicle sin azúcar o chupar caramelos sin azúcar

Sentirse mal (náuseas) o vomitar (vómitos), malestar estomacal

Mantente con alimentos simples. Intenta tomar las tabletas después de las comidas

Estreñimiento

Come una dieta equilibrada y bebe mucha agua cada día

Mood changes, changes to the way things taste, feeling shaky, itchy rash, sweating, high temperature (fever)

Si es problemático, hable con su médico

Importante: if you feel depressed or start having thoughts about harming yourself, you must let your doctor know de inmediato. Depression can occur as a symptom of nicotine withdrawal and it can also on occasion occur as a result of taking bupropion.

En raras ocasiones, los medicamentos que afectan el nivel de serotonina en el cerebro pueden hacer que este suba demasiado y cause problemas. El riesgo es mayor si está tomando más de un medicamento con este efecto. Busque atención médica si desarrolla alguna combinación de los siguientes síntomas:

  • Músculos rígidos o movimientos 'bruscos'.

  • Latidos del corazón inusualmente rápidos.

  • Alta temperatura (fiebre), sensación de malestar (náuseas) o estar enfermo (vómitos), diarrea.

  • Sentirse delirante o ver visiones (alucinar).

Si experimenta cualquier otro síntoma que crea que puede deberse a las tabletas, hable con su médico o farmacéutico para obtener más consejos.

How to store bupropion

  • Mantenga todos los medicamentos fuera del alcance y la vista de los niños.

  • Almacenar en un lugar fresco y seco, lejos del calor y la luz directos.

Información importante sobre todos los medicamentos

Información importante sobre todos los medicamentos

Nunca tome más de la dosis prescrita. Si sospecha que usted u otra persona podría haber tomado una sobredosis de este medicamento, acuda al departamento de accidentes y emergencias de su hospital local. Lleve el envase con usted, incluso si está vacío.

Este medicamento es para ti. No lo des a otros, incluso si su condición parece ser la misma que la tuya.

Si estás recibiendo algún tratamiento médico, informa a la persona que lo realiza sobre los medicamentos que estás tomando.

No guardes medicamentos caducados o no deseados. Llévalos a tu farmacia local, donde se encargarán de desecharlos por ti.

Si tienes alguna pregunta sobre tus medicamentos, consulta a tu farmacéutico.

MHRA - Reporte de reacciones adversas

Informe los efectos secundarios sospechosos de medicamentos, vacunas, cigarrillos electrónicos, incidentes con dispositivos médicos, productos defectuosos o falsificados (falsos) a la Agencia Reguladora de Medicamentos y Productos Sanitarios para garantizar un uso seguro y efectivo.

Preguntas frecuentes

Can I stop smoking without additional support if I'm taking bupropion?

Bupropion helps with the physical withdrawal symptoms, but it does not make you stop smoking on its own. You still need determination to break the habit. Combining bupropion with counselling from a health professional significantly increases your chances of success. Most doctors will only prescribe bupropion as part of a structured 'stopping smoking' programme.

What if I miss a scheduled dose of bupropion?

If you forget to take a dose, you should skip the missed dose. Do not take two doses together to try and catch up. Simply take your next scheduled dose when it is due.

Should I be concerned about my blood pressure while taking bupropion?

Yes, your blood pressure needs to be checked regularly while you are taking bupropion. In some people, blood pressure can increase as a side effect.

What should I do if I've been taking bupropion for seven weeks and I am still smoking?

If you are still smoking after seven weeks of treatment, you should inform your doctor. They will then discuss the available options with you.

Will bupropion interact with other medicines I'm taking, especially non-prescription ones?

Yes, it's very important to tell your doctor about all medicines you are taking, including those bought without a prescription, and any herbal or complementary medicines. For instance, if you are taking digoxin for a heart condition, its dose may need adjustment. Also, when you quit smoking, your body's way of processing certain medicines can change, so other prescribed medicine doses might need adjusting.

How long will I be taking bupropion for in total?

A full course of treatment with bupropion typically lasts for 7-9 weeks. After this period, your doctor might suggest gradually reducing your dose over a few days before you completely stop taking the tablets.

Lecturas adicionales y referencias

Historial del artículo

La información en esta página está escrita y revisada por pares por clínicos calificados.
  • Próxima revisión: 8 de noviembre de 2026
  • 9 Nov 2023 | Última versión

    Última actualización por

    Michael Stewart, MRPharmS

    Revisado por

    Sid Dajani

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