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Aprepitant para prevenir el mareo

Emend

Aprepitant is an anti-sickness medicine. It is taken alongside other medicines to help stop sickness (nausea and vomiting) after chemotherapy.

Take one 125 mg capsule an hour before chemotherapy, and then one 80 mg capsule each morning for the following two days.

The most common side-effects are hiccups, indigestion, constipation and headache.

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About aprepitant

Tipo de medicamento

Neurokinin-receptor antagonist anti-sickness medicine

Usado para

Prevention of sickness (nausea and vomiting) associated with chemotherapy

También llamado

Emend®

Disponible como

Capsules, oral powder sachets

Aprepitant is known as a neurokinin-receptor antagonist. It is prescribed alongside other medicines (dexametasona and 5HT3-receptor antagonists such as ondansetrón) to help stop you from feeling or being sick after quimioterapia. It works by blocking the effect of a naturally produced chemical, called 'substance P'.

Before taking aprepitant

Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking aprepitant it is important that your doctor knows:

  • Si estás embarazada o amamantando.

  • Si tienes algún problema con el funcionamiento de tu hígado.

  • Si alguna vez has tenido una reacción alérgica a un medicamento.

  • If you have a rare, inherited blood disorder called porphyria.

  • If you are taking any other medicines, including any medicines you are taking which are available to buy without a prescription, as well as herbal and complementary medicines. Aprepitant interferes with a number of other medicines, including the 'pill' and the 'mini pill'.

How to take aprepitant

  • Before you start treatment, read the manufacturer's printed information leaflet from inside your pack. The manufacturer's leaflet will give you more information about aprepitant and a full list of side-effects which you may experience from taking it.

  • Take aprepitant capsules exactly as your doctor tells you to. You will be asked to take one 125 mg capsule one hour before your chemo treatment starts, and then one 80 mg capsule each morning for the following two days.

  • Swallow the capsules whole - it may help to take your doses with a drink of water. It is not important whether you take the capsules before or after food.

  • If your child has been prescribed oral powder sachets, the dose will be prepared and given to your child by a doctor or nurse in hospital.

  • If you forget to take a dose, contact your doctor for advice about what to do. Do not take two doses together to make up for a missed one.

Obteniendo el máximo de tu tratamiento

  • Even if you do not feel like eating or drinking, try to sip water regularly to prevent you from becoming lacking in fluid in the body (dehydrated).

  • Rather than trying to eat three main meals a day, try eating small, simple but nourishing snacks, every few hours.

  • If you are using hormonal contraception (this includes the 'pill' and the 'mini pill'), additional contraceptive precautions such as a condom will be required while you are on aprepitant, and for two months afterwards. If you need further advice about this, speak with your doctor or pharmacist.

  • If you buy any medicines, check with a pharmacist that they are suitable to take with your other medicines. This is because many other medicines can interfere with aprepitant and therefore may not be recommended for you.

Can aprepitant cause problems?

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with aprepitant. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.

Common aprepitant side-effects - these affect fewer than 1 in 10 people who take this medicine


¿Qué puedo hacer si experimento esto?

Dolor de cabeza

Bebe mucha agua y pide a un farmacéutico que te recomiende un analgésico adecuado. Si los dolores de cabeza continúan, informa a tu médico

Sintiéndose cansado, somnoliento o mareado

Do not drive and do not use tools or machines if affected

Estreñimiento

Try to eat a well-balanced diet, and drink several glasses of water each day

Loss of appetite, hiccups, indigestion

Si es problemático, hable con su médico

Cambios en algunos análisis de sangre

Su médico verificará esto

Si experimenta otros síntomas que cree que pueden deberse a este medicamento, hable con su médico o farmacéutico.

How to store aprepitant

  • Mantenga todos los medicamentos fuera del alcance y la vista de los niños.

  • Almacenar en un lugar fresco y seco, lejos del calor y la luz directos.

Información importante sobre todos los medicamentos

Información importante sobre todos los medicamentos

Nunca tome más de la dosis prescrita. Si sospecha que usted u otra persona podría haber tomado una sobredosis de este medicamento, acuda al departamento de accidentes y emergencias de su hospital local. Lleve el envase con usted, incluso si está vacío.

Este medicamento es para ti. Nunca lo des a otras personas, incluso si su condición parece ser la misma que la tuya.

Si vas a someterte a una operación o a un tratamiento dental, informa a la persona que realiza el tratamiento sobre los medicamentos que estás tomando.

No guardes medicamentos caducados o no deseados. Llévalos a tu farmacia local, donde se encargarán de desecharlos por ti.

Si tienes alguna pregunta sobre este medicamento, consulta a tu farmacéutico.

Informar efectos secundarios de un medicamento o vacuna

Si experimenta efectos secundarios, puede reportarlos en línea a través de Sitio web de Yellow Card.

Preguntas frecuentes

What is 'substance P' and why does blocking it help with sickness?

Aprepitant works by blocking a natural chemical in your body called 'substance P'. This chemical is involved in the signals that cause nausea and vomiting, especially after chemotherapy. By blocking its effect, aprepitant helps to prevent these unwanted symptoms.

Can I take aprepitant if I have liver problems?

If you have any problems with how your liver works, it's important to tell your doctor before starting aprepitant. They will need to know this information to determine if aprepitant is suitable for you or if extra care needs to be taken during your treatment.

What should I do if I forget to take a dose of aprepitant?

If you miss a dose of aprepitant, you should contact your doctor for advice on what to do. It is important not to take two doses together to try and make up for the one you missed.

Why is it important to prevent dehydration while taking aprepitant?

Chemotherapy can make you feel unwell, and it's easy to become dehydrated, meaning you lack enough fluid in your body. Even if you don't feel like eating or drinking, regularly sipping water is important to prevent dehydration, which can make you feel even worse.

Are there any specific dietary recommendations while taking aprepitant?

While taking aprepitant, instead of trying to eat three large meals a day, it's often more helpful to try eating small, simple, but nourishing snacks every few hours. This can be easier to manage when you're feeling unwell.

Lecturas adicionales y referencias

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