Colirios de antazolina y xilometazolina
Otrivine-Antistin
Peer reviewed by Sid DajaniLast updated by Michael Stewart, MRPharmSLast updated 6 May 2024
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Otrivine-Antistin® drops relieve eye itching and redness associated with allergies.
Use one drop two or three times a day in both eyes. Do not use the drops for more than seven days.
When first put in, eye drops can cause blurred vision. Wait until this clears before you drive.
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About antazoline and xylometazoline eye drops
Tipo de medicamento | Colirio antialérgico |
Utilizado para | Para aliviar los síntomas oculares de alergias como la fiebre del heno |
También llamado | Otrivine-Antistin® |
Disponible como | Gotas oculares |
The drops contain two ingredients. Antazoline is an antihistamine; it helps relieve allergic itchiness by blocking the release of a chemical called histamine, which is produced by the body as part of an allergic reaction. Xylometazoline is a sympathomimetic agent; it works on the blood vessels in the eye to reduce redness. Antazoline and xylometazoline eye drops (brand name Otrivine-Antistin®) are used to treat allergic conjunctivitis.
Allergic conjunctivitis causes red, watery and itchy eyes. It is caused by exposure to irritants such as plant pollens, pet fur, cosmetics or house dust mite. Seasonal allergic conjunctivitis occurs at certain times in a year, a common cause being an allergy to pollen in the hay fever season. Perennial allergic conjunctivitis persists throughout the year. This is commonly due to an allergy to house dust mite or animal hair. Antazoline and xylometazoline eye drops are available on prescription, or you can buy them without a prescription at a pharmacy. They can be used by adults and by children over 12 years of age.
Before using antazoline and xylometazoline eye drops
Para asegurarse de que éste es el tratamiento adecuado para usted, antes de empezar a utilizar el colirio es importante que su médico o farmacéutico lo sepan:
Si usa lentes de contacto blandas.
If you have any of the following: high blood pressure, an overactive thyroid gland, diabetes, increased pressure in your eye (glaucoma), heart or blood vessel disease, difficulty passing urine, or a tumour on your adrenal glands, called phaeochromocytoma.
If you are pregnant or breastfeeding. This is because, while you are expecting or feeding a baby, you should only use medicines on the recommendation of a doctor.
If you have ever had an allergic reaction to an antihistamine or to any eye drops.
Si toma o utiliza otros medicamentos. Esto incluye cualquier medicamento que esté tomando y que pueda adquirirse sin receta, así como medicamentos a base de plantas y complementarios.
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How to use antazoline and xylometazoline eye drops
Lávese bien las manos antes de utilizar las gotas.
Quita la tapa.
Inclina un poco la cabeza hacia atrás y tira del párpado inferior del ojo hacia fuera para formar una bolsa.
Sostenga la botella boca abajo cerca del ojo. Procure no tocarse el ojo mientras lo hace.
Gently squeeze the bottle to release one drop into your eye. Only use a second drop if the first drop missed going into your eye.
Cierre el ojo durante uno o dos minutos y presione suavemente en el lado de la nariz donde el rabillo del ojo se une con la nariz. Esto ayuda a evitar que la gota se escurra y la mantiene en el ojo.
Repeat the process in your other eye.
Vuelva a colocar la tapa.
Aproveche al máximo su tratamiento
Antes de empezar a usar el colirio, lea el prospecto impreso del envase. Le dará más información sobre las gotas y le proporcionará una lista completa de los efectos secundarios que puede experimentar con su uso.
Use the eye drops two or three times a day in both eyes, unless you have been told otherwise by your doctor.
Tenga cuidado de no tocarse el ojo, los dedos o cualquier otra superficie con el cuentagotas de la botella. Esto podría infectar el líquido que queda en el frasco.
When you first put the drops into your eye, it may cause blurred vision. This should quickly clear, but make sure you can see clearly again before you drive and before using machines or tools.
If you are using any other eye drops, leave 5-10 minutes between using the other eye drops. This is to prevent more liquid going into your eye than it can handle. Otherwise the drops will overflow from your eye and not have the intended effect.
Do not wear soft contact lenses while you are using the eye drops unless your doctor has advised you otherwise. This is because lenses will irritate your eyes, and also because there is a preservative in the drops which can affect soft contact lenses.
If your symptoms do not improve within a few days, or if they become worse, make an appointment to see a doctor.
Your doctor will tell you how long to use the drops for. You should notice an improvement in your symptoms within a few days, but treatment for up to seven days is sometimes required. Do not use the drops for more than seven consecutive days.
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Can antazoline and xylometazoline eye drops cause problems?
Along with their useful effects, eye drops can cause unwanted side-effects although not everyone experiences them. The table below contains the most common one associated with antazoline and xylometazoline eye drops. You will find a full list in the manufacturer's information leaflet supplied with your drops. Unwanted effects often improve as your body adjusts to a new medicine, but speak with your doctor or pharmacist if the following continues or becomes troublesome.
Antazoline and xylometazoline eye drop side-effects | ¿Qué puedo hacer si me ocurre esto? |
Mild eye discomfort (such as burning or stinging) | This usually disappears within a few minutes of using the drops. Do not drive and do not use tools or machines unless your vision is clear |
Occasionally people can be allergic to eye drops, particularly when the eye drops contain a preservative. If you notice a rash around your eyes, or any swelling or increased itching, stop using the drops and contact a doctor for advice. If you experience any other symptoms which you think may be due to the eye drops, speak with your doctor or pharmacist for further advice.
How to store antazoline and xylometazoline eye drops
Mantenga todos los medicamentos fuera del alcance y de la vista de los niños.
Almacenar en un lugar fresco y seco, lejos del calor y la luz directos.
Eye drops only keep for four weeks once the bottle has been opened so throw away the bottle after you have finished the course of treatment, even if there is some solution left. Never keep opened bottles of eye drops to use later. This helps to prevent the risk of eye infections.
Información importante sobre todos los medicamentos
Información importante sobre todos los medicamentos
Si compra algún medicamento, compruebe con el farmacéutico que es seguro utilizarlo con sus otros medicamentos.
No utilice nunca una dosis superior a la recomendada.
Si sospecha que alguien ha ingerido este medicamento por accidente, póngase en contacto con el servicio de urgencias de su hospital local para que le asesoren.
Si va a someterse a una operación o a un tratamiento dental, comunique a la persona que lleve a cabo el tratamiento qué medicamentos está utilizando.
Este medicamento es para usted. Nunca se lo dé a otras personas aunque su enfermedad parezca ser la misma que la suya.
No guarde medicamentos caducados o que no desee. Llévelos a su farmacia local, que se encargará de eliminarlos por usted.
Si tiene cualquier duda sobre este medicamento pregunte a su farmacéutico.
MHRA - Notificación de reacciones adversas
Notifique a la Agencia Reguladora de Medicamentos y Productos Sanitarios las sospechas de efectos secundarios de medicamentos, vacunas, cigarrillos electrónicos, incidentes con productos sanitarios o productos defectuosos o falsificados para garantizar un uso seguro y eficaz.
Lecturas complementarias y referencias
- Manufacturer's PIL, Otrivine-Antistin® Eye Drops; Thea Pharmaceuticals Ltd, The electronic Medicines Compendium. Dated December 2021.
- Medicamentos BNF completa 89ª edición; Asociación Médica Británica y Real Sociedad Farmacéutica de Gran Bretaña, Londres.
Historia del artículo
La información de esta página ha sido redactada y revisada por médicos cualificados.
Fecha de la próxima revisión: 31 de marzo de 2027
6 May 2024 | Latest version

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