Can I take Metformin and Quetiamine together?
Drug interaction guide
Originally published 25 Jan 2026
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Taking quetiapine may make your metformin less effective at controlling your blood sugar levels. This can lead to higher blood sugar (hyperglycaemia).
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Why this happens
Quetiapine is an antipsychotic medication that can interfere with how your body handles insulin and sugar. It can cause the body to become less sensitive to insulin or reduce the amount of insulin produced, which directly opposes the blood-sugar-lowering effects of metformin.
What you should do
You should monitor your blood sugar levels more frequently when starting, stopping, or changing the dose of quetiapine. If you notice your blood sugar readings are consistently high, or if you experience increased thirst or frequent urination, contact your doctor. They may need to adjust your metformin dose.
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Using other medicines
Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Descargo de responsabilidad
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Historia del artículo
La información de esta página ha sido redactada y revisada por médicos cualificados.
25 Enero 2026 | Publicado originalmente
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