Can I take Candesartan and Eplerenone together?

Por qué sucede esto

Both candesartan and eplerenone work by affecting a hormone system in the body that regulates salt and water balance. Specifically, they both cause the kidneys to keep hold of potassium rather than flushing it out in the urine. When used together, this 'potassium-sparing' effect is doubled.

You must speak to your doctor before taking these together. If prescribed both, your doctor will need to monitor your kidney function and potassium levels very closely with regular blood tests. Seek medical help immediately if you experience muscle weakness, tingling sensations, or an irregular heartbeat. Avoid using salt substitutes containing potassium (such as Lo-Salt) while taking these medicines.

Embarazo

You must not take these medicines if you are pregnant or planning to become pregnant. They can cause serious harm or death to an unborn baby, particularly if used during the second and third trimesters.

High potassium levels (Hyperkalaemia)

Both medicines increase potassium levels in your blood. You must avoid using potassium supplements or salt substitutes containing potassium, as dangerously high levels can cause life-threatening heart rhythm problems.

Kidney function and NSAID use

Taking anti-inflammatory painkillers (like ibuprofen or naproxen) while on these medicines can significantly increase the risk of sudden kidney failure. Check with a pharmacist before using any over-the-counter pain relief.

Alcohol

Drinking alcohol while taking these medicines can cause your blood pressure to drop too low. This may make you feel dizzy, lightheaded, or faint, especially when standing up. It is best to keep your alcohol intake within recommended limits and see how the medicine affects you first.

Jugo de toronja

You should avoid drinking large amounts of grapefruit juice. Grapefruit contains compounds that can increase the level of eplerenone in your blood, which may increase the risk of side effects.

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Descargo de responsabilidad

Esta información es solo para fines educativos generales y no debe considerarse como un sustituto del consejo médico profesional. Siempre consulte a su médico de cabecera, farmacéutico u otro profesional de la salud calificado antes de tomar decisiones sobre sus medicamentos. Las circunstancias individuales pueden variar, y solo un profesional de la salud que conozca su historial médico puede proporcionar orientación personalizada.