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Can I take Azathioprine and Valsartan together?

Drug interaction guide

Taking these two medicines together can increase the risk of your white blood cell count dropping too low (a condition called leucopenia) or cause a significant drop in red blood cells (anaemia). This can make you more likely to catch infections or feel very tired and weak.

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Why this happens

Both azathioprine and valsartan can affect the bone marrow's ability to produce blood cells. Azathioprine suppresses the immune system, and ACE inhibitors or ARBs (like valsartan) can interfere with the production of red blood cells. When used together, these effects can add up.

You must speak to your doctor before taking these together. If you are prescribed both, your doctor will likely need to perform more frequent blood tests to monitor your full blood count. Contact your doctor immediately if you develop signs of infection (such as a fever, sore throat, or mouth ulcers) or unusual bruising or bleeding.

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Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.

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Article history

The information on this page is written and peer reviewed by qualified clinicians.

  • 12 May 2026 | Originally published
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