Can I take Amlopidine and Omega together?
Drug interaction guide
Originally published 14 Mar 2026
Meets Patient’s editorial guidelines
- DownloadDownload
- Share
- Language
- Discussion
- Audio Version
Taking amlodipine and omega-3 (fish oil) together may cause your blood pressure to drop lower than intended. This can sometimes lead to symptoms like dizziness, lightheadedness, or feeling faint, especially when standing up quickly.
In this article:
Video picks for Drug interactions
Continue reading below
Why this happens
Both amlodipine and omega-3 fatty acids have blood-pressure-lowering effects. Amlodipine works by relaxing your blood vessels, while omega-3 can also reduce blood pressure through various natural pathways. When used together, their effects can add up (an additive effect).
What you should do
Back to contentsIt is generally safe to take these together, but you should monitor your blood pressure regularly at home. If you feel dizzy, lightheaded, or unusually tired, speak to your doctor. They may need to adjust your amlodipine dose. Do not stop taking your prescribed medication without consulting a healthcare professional.
Continue reading below
Important precautions
Back to contentsBleeding disorders or use of blood thinners (e.g. warfarin)
High doses of omega-3 can increase your risk of bleeding. If you take blood-thinning medication or have a bleeding disorder, you must be monitored for signs of bruising or bleeding.
Food and drink warnings
Back to contentsHigh-fat meals
Taking omega-3 supplements with a meal that contains fat helps your body absorb the medicine much better. It is recommended to take them with your largest meal of the day.
Continue reading below
Using other medicines
Back to contentsTaking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
Patient picks for Drug interactions
Treatment and medication
Can I take Ramipril and Sertraline together?
Taking ramipril and sertraline together can occasionally cause the level of sodium in your blood to drop too low (a condition called hyponatraemia). This can make you feel tired, confused, or dizzy, and in rare cases, it can be serious. Additionally, both medicines can slightly increase the risk of bleeding, particularly in the stomach.
Treatment and medication
Can I take Pregabalin and Trazodone together?
Taking pregabalin and trazodone together can make you feel very sleepy, dizzy, and unsteady on your feet. It can also slow down your thinking and reaction times, and in some cases, it may cause breathing difficulties.
Continue reading below
Article history
The information on this page is written and peer reviewed by qualified clinicians.
14 Mar 2026 | Originally published
Ask, share, connect.
Browse discussions, ask questions, and share experiences across hundreds of health topics.
Feeling unwell?
Assess your symptoms online for free
Sign up to the Patient newsletter
Your weekly dose of clear, trustworthy health advice - written to help you feel informed, confident and in control.
By subscribing you accept our Privacy Policy. You can unsubscribe at any time. We never sell your data.