Can I take Amlopidine and Magnesium together?
Drug interaction guide
Originally published 14 Mar 2026
Meets Patient’s editorial guidelines
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Taking amlodipine and magnesium together may cause your blood pressure to drop lower than intended. This can lead to symptoms like dizziness, lightheadedness, or feeling faint. In some cases, it may also cause a very slow or irregular heartbeat.
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Why this happens
Both amlodipine and magnesium work by relaxing the muscles in your blood vessels and heart. Amlodipine is a 'calcium channel blocker', and magnesium acts as a natural calcium blocker. When used together, they can have an 'additive effect', meaning they strengthen each other's ability to lower blood pressure and slow the heart.
What you should do
Back to contentsIt is usually safe to take these together, but you should monitor your blood pressure regularly. If you feel dizzy, especially when standing up, or notice your heart rate is unusually slow, speak to your GP. If you are taking high-dose magnesium supplements or using magnesium intravenously, your doctor may need to adjust your amlodipine dose.
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Important precautions
Back to contentsKidney disease
If you have severe kidney impairment, your body cannot remove excess magnesium. This can lead to dangerously high levels in the blood, affecting your heart rhythm and breathing.
Food and drink warnings
Back to contentsDairy products (Milk, Cheese, Yoghurt)
Dairy products are high in calcium. Calcium can compete with magnesium for absorption in the gut. If you take a magnesium supplement, try to take it at least 2 hours apart from eating large amounts of dairy to ensure you get the full benefit of the mineral.
Alcohol
Alcohol can lower your blood pressure. Taking amlodipine with alcohol may cause you to feel dizzy, lightheaded, or faint. Additionally, chronic alcohol consumption can cause the body to lose magnesium through urine, potentially making a magnesium deficiency worse.
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Using other medicines
Back to contentsTaking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Article history
The information on this page is written and peer reviewed by qualified clinicians.
14 Mar 2026 | Originally published

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