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Can I take Alendronic acid and Evacal together?

Drug interaction guide

Taking Evacal (calcium and vitamin D) at the same time as alendronic acid can stop the alendronic acid from being absorbed into your body. This means the medicine for your bones will not work properly.

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Why this happens

Alendronic acid is very sensitive to other substances in the stomach. Calcium binds to the alendronic acid, creating a large 'clump' that the body cannot absorb into the bloodstream.

You must wait at least 30 minutes after taking your alendronic acid before taking your Evacal or any other food, drink, or supplements. Most doctors recommend taking alendronic acid first thing in the morning on an empty stomach, and then taking your Evacal later in the day (for example, at lunchtime or in the evening).

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Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.

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Article history

The information on this page is written and peer reviewed by qualified clinicians.

  • 14 Mar 2026 | Originally published
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