Can I take Accrete d3 and Perfectil together?
Drug interaction guide
Originally published 14 Mar 2026
Meets Patient’s editorial guidelines
- DownloadDownload
- Share
- Language
- Discussion
- Audio Version
Taking both Accrete D3 and Perfectil together can lead to you taking too much Vitamin D and Calcium. This can cause high levels of calcium in your blood (hypercalcaemia), which may lead to symptoms like nausea, constipation, thirst, or in more serious cases, kidney stones.
In this article:
Video picks for Drug interactions
Continue reading below
Why this happens
Both products contain Vitamin D and Calcium. Accrete D3 is a high-dose supplement (usually 1000mg Calcium / 880 units Vitamin D), and Perfectil also contains these ingredients. Taking them together creates an 'additive effect', meaning the doses add up and may exceed the safe daily limit.
What you should do
Back to contentsYou should speak to your doctor or pharmacist before taking these together. They may advise you to stop the Perfectil or switch to a different multivitamin that does not contain extra calcium and Vitamin D, especially if you have a history of kidney stones or kidney problems.
Continue reading below
Using other medicines
Back to contentsTaking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
Patient picks for Drug interactions

Treatment and medication
Can I take Abrysvo powder and Inhalation powder. together?
There is no known direct interaction between the Abrysvo vaccine and inhaled medicines (inhalation powders). However, if you are unwell or have a fever, you may need to delay your vaccination.

Treatment and medication
Can I take Codeine and Magnesium together?
Taking magnesium and codeine together can lead to increased drowsiness and may cause constipation. Magnesium can also slightly interfere with how your body absorbs codeine if taken at the exact same time.
Continue reading below
Article history
The information on this page is written and peer reviewed by qualified clinicians.
14 Mar 2026 | Originally published

Ask, share, connect.
Browse discussions, ask questions, and share experiences across hundreds of health topics.

Feeling unwell?
Assess your symptoms online for free
Sign up to the Patient newsletter
Your weekly dose of clear, trustworthy health advice - written to help you feel informed, confident and in control.
By subscribing you accept our Privacy Policy. You can unsubscribe at any time. We never sell your data.