Can I take Accrete d3 and Femara together?
Drug interaction guide
Originally published 14 Mar 2026
Meets Patient’s editorial guidelines
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Accrete D3 (calcium and vitamin D3) and Femara (letrozole) do not have a harmful interaction. In fact, they are often prescribed together because Femara can cause bone thinning (osteoporosis), and Accrete D3 helps to strengthen bones and reduce the risk of fractures.
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Why this happens
Femara works by lowering oestrogen levels, which can lead to a loss of bone mineral density. Accrete D3 provides the essential building blocks (calcium and vitamin D) to help maintain bone health during this treatment. There are no known issues with how these medicines are absorbed or processed by the body when taken together.
What you should do
Back to contentsIt is safe and often beneficial to take these two medications together. You should follow the dosage instructions provided by your doctor. To get the most benefit, try to take your Accrete D3 at the same time each day, ideally with a meal to help your body absorb the calcium.
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Using other medicines
Back to contentsTaking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Article history
The information on this page is written and peer reviewed by qualified clinicians.
14 Mar 2026 | Originally published
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