Can I take Abiraterone and Sulforaphane together?

Why this happens

Abiraterone is broken down in the liver by a specific protein called CYP3A4. Sulforaphane can 'switch on' or increase the activity of this protein. This causes your body to process and remove abiraterone much faster than intended, leading to lower levels of the medicine in your system.

You should avoid taking sulforaphane supplements while you are being treated with abiraterone. If you are already taking these supplements, speak to your doctor or oncologist before stopping or changing your routine. It is generally fine to eat normal amounts of broccoli as part of a balanced diet, but concentrated supplements should be avoided.

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.