Can I take 2.5mg and Magnesium malate together?
Drug interaction guide
Originally published 14 Mar 2026
Meets Patient’s editorial guidelines
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Magnesium malate may interfere with how your body absorbs Eliquis (apixaban), potentially making the blood thinner less effective. Additionally, high doses of magnesium can sometimes have a very mild blood-thinning effect of their own, which could theoretically increase the risk of bruising or bleeding when taken with Eliquis.
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Why this happens
Magnesium is a multivalent cation that can bind to certain medications in the digestive tract (chelation), reducing the amount of medicine that enters the bloodstream. Furthermore, magnesium may have minor anti-platelet effects that could add to the effect of Eliquis.
What you should do
Back to contentsTo be safe, space these two out by at least 2 hours. Take your Eliquis first, then wait 2 hours before taking your magnesium supplement. If you notice any unusual bruising, nosebleeds, or bleeding gums, speak to your doctor. Do not stop taking your prescribed Eliquis without medical advice.
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Using other medicines
Back to contentsTaking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Article history
The information on this page is written and peer reviewed by qualified clinicians.
14 Mar 2026 | Originally published
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