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Cannabis Compound

Un químico encontrado en el cannabis podría ser más efectivo que los analgésicos

Los investigadores descubren cómo la planta de cannabis crea moléculas que alivian el dolor y que son 30 veces más potentes para reducir la inflamación que la aspirina.

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If you have a diagnosed condition and standard treatments haven’t worked, you may be eligible for specialist-prescribed medical cannabis in the UK. Verifica tu elegibilidad

As interest in medical cannabis continues to grow, experts at the University of Guelph, Canada have found chemical compounds in the plant (called flavanoids) which could be 30 times more effective than simple painkillers.

Flavanoids are the pigment (colour) found in all plants which contain antioxidants. In cannabis plants, two flavonoids, called cannflavin A and cannflavin B, appear to have anti-inflammatory properties.

The scientists applied various biochemistry techniques to find out which cannabis genes were required to create these chemicals. The findings are published in the journal Phytochemistry.

Cannflavins were first discovered as early as 1985, but only now has research emerged on how they are in made in the plant.

"There's clearly a need to develop alternatives for relief of acute and chronic pain that go beyond opioids," said Professor Tariq Akhtar, lead author of the research. "These molecules are non-psychoactive and they target the inflammation at the source, making them ideal painkillers."

Cannflavins may have fewer side effects than strong painkillers such as opioids.

However, because cannabis plants only contain a small number of flavonoids naturally, patients would need to consume large amounts for the anti-inflammatory properties to work.

Professor Steven Rothstein who co-authored the research said: "We are now working to develop a biological system to create these molecules, which would allow us the opportunity to engineer large quantities."

The University of Guelph is now working with a biotechnology company to patent a way of extracting the flavonoids from cannabis plants to make a commercial form of pain relief.

Preguntas frecuentes

What are flavonoids, and are they unique to cannabis?

Flavanoids are the natural pigments responsible for giving plants their colour. They are present in all plants and are known for containing antioxidants. In cannabis plants specifically, two types called cannflavin A and cannflavin B have been identified as having anti-inflammatory effects.

Can cannflavins make me feel 'high'?

No, cannflavins are described as non-psychoactive. This means they do not produce the 'high' sensation associated with some other compounds found in cannabis.

How do cannflavins help with pain?

Cannflavins are believed to relieve pain by targeting inflammation directly at its source. This anti-inflammatory action makes them potentially effective painkillers.

When were cannflavins first identified?

Cannflavins were initially discovered as early as 1985. However, the recent research from the University of Guelph is the first to explain how these chemicals are produced within the cannabis plant.

Will I eventually be able to get medicine made from these cannabis compounds?

Researchers are currently working to develop a system to create large quantities of these molecules. The University of Guelph is also collaborating with a biotechnology company to patent a method for extracting cannflavins from cannabis plants to produce a commercial form of pain relief.

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Ashwin Bhandari

Redactor Médico

Licenciatura en Periodismo

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Natalie Healey

Periodista freelance

Licenciatura (Hons) en Ciencias Biomédicas

Es una periodista de salud con sede en Londres que ha estado escribiendo sobre ciencia y medicina durante varios años. Es la exjefa de redacción en Patient.

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