Malabsorción gastrointestinal
Revisado por pares por Dr Colin Tidy, MRCGPÚltima actualización por Dr Hayley Willacy, FRCGP Last updated 30 Nov 2022
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En esta serie:Enfermedad celíacaDermatitis herpetiforme
Gastrointestinal malabsorption syndrome means a failure to fully absorb digested foods from the gut (bowel) into your body. There are many different causes. Prolonged intestinal malabsorption may cause problems because of a lack of carbohydrates, proteins, fats, minerals and vitamins that are essential to keep you healthy.
The treatment will depend on the cause of malabsorption but will also include supplements and other ways to make up for the reduced amount of carbohydrate, protein, fat, minerals and vitamins getting into your gastrointestinal tract.
At a glance
Gastrointestinal malabsorption is when your gut cannot absorb nutrients from food properly.
Symptoms include tiredness, weight loss, and chronic diarrhoea.
Stools may be pale, bulky, smelly, and difficult to flush.
It can lead to deficiencies like iron, folate, and vitamin B12 deficiency.
Common causes in the UK include coeliac disease, Crohn's disease, and chronic pancreatitis.
Treatment focuses on the underlying cause and nutritional support.
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What are the symptoms of gastrointestinal malabsorption?
There may be no symptoms if the malabsorption is mild and has not continued for very long. More severe or persistent malabsorption may lead to:
Cansancio (fatiga)
This is because of a lack of energy as you are not absorbing nutrients and essential vitamins and minerals from food.
Pérdida de peso
If you can't absorb enough energy (calories) from your food then this will cause you to lose weight (and may cause poor growth in children).
Persistent (chronic) diarrhoea
This is a common symptom of persistent malabsorption.
Pale, bulky and smelly stools (steatorrhoea)
This is because there is excessive fat in the stools and they become pale, bulky and very smelly. Fatty stools float and are difficult to flush away. They often leave a greasy rim around the pan.
Intestinal malabsorption may also cause:
Abnormal bleeding, caused by low vitamin K.
Edema, which occurs because of insufficient protein and calories absorbed into the body.
There may also be other symptoms due to the particular underlying condition that is causing the malabsorption.
What are the causes of gastrointestinal malabsorption?
Volver al contenidoThe most common causes in the UK are enfermedad celíaca, enfermedad de Crohn and chronic pancreatitis. However, the malabsorption of simple carbohydrates affects about 1 in 4 people in Europe. Some diseases associated with malabsorption are found more often in some families - for example, coeliac disease, Crohn's disease, fibrosis quística and lactose intolerance.
The causes of gastrointestinal malabsorption include:
Problems with absorbing food from the gut (bowel) into your body
Enfermedad celíaca - a long-term disease that mostly affects the small intestine.
Soya milk intolerance.
Fructose intolerance.
Infection - for example, intestinal tuberculosis, la diarrea del viajero.
Immune deficiency - for example, infección por VIH.
Pancreatic insufficiency - for example, fibrosis quística, pancreatitis crónica, cáncer de páncreas.
Structural causes
Malabsorption may be cause by loss of part of the bowel that is essential to absorb the broken down (digested) food into the body - for example:
Removal of the stomach or part of the bowel after a stomach or bowel operation.
Causes outside the bowel
Ejemplos incluyen:
Eating disorders: anorexia nerviosa, bulimia nerviosa.
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¿Qué pruebas se necesitan?
Volver al contenidoInitial tests will include análisis de sangre y stool tests. Further tests may include an abdominal ultrasonido, barium studies and a tomografía computarizada (TC) o una escaneo de resonancia magnética (IRM). Any further tests will depend on the likely underlying cause of the intestinal malabsorption.
What are the treatments for gastrointestinal malabsorption?
Volver al contenidoThe treatment will mainly depend on the underlying cause of the malabsorption. However, treatment will also be needed to increase the amount of essential nutrients in the body, including carbohydrates, proteins, fats, minerals and fat-soluble vitamins (nutritional support).
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Preguntas frecuentes
Can mild malabsorption be present without me noticing any symptoms?
Yes, if the malabsorption is mild and has not been ongoing for a long time, you might not experience any noticeable symptoms.
Why would I feel tired if I have malabsorption?
Tiredness, or fatigue, can occur because your body isn't absorbing enough essential nutrients, vitamins, and minerals from your food. This means you don't have enough energy.
What kind of problems can malabsorption cause with my stools?
Malabsorption can lead to persistent (chronic) diarrhoea. You might also notice that your stools are pale, bulky, very smelly, and difficult to flush away. These fatty stools often float and can leave a greasy ring around the toilet bowl.
Could malabsorption affect my bones or cause unusual bleeding?
Yes, malabsorption can lead to several specific deficiencies. This includes vitamin D deficiency, which can cause rickets and osteomalacia (softening of bones), and low vitamin K, which can result in abnormal bleeding.
Is it possible for malabsorption to cause swelling in my body?
Yes, malabsorption can cause oedema, which is swelling. This happens if your body isn't absorbing enough protein and calories.
I've heard of coeliac disease and Crohn's disease, but what are some other common causes of malabsorption?
Besides coeliac disease and Crohn's disease, chronic pancreatitis is another common cause in the UK. Globally, problems with absorbing simple carbohydrates affect a significant number of people. Other causes can include various intolerances like lactose, cow's milk protein, or fructose, infections like traveller's diarrhoea, or immune deficiencies such as HIV.
Can surgery on my digestive system lead to malabsorption?
Yes, if part of your stomach or bowel is removed during surgery, it can lead to malabsorption. This is because these parts are essential for absorbing digested food into your body.
Lecturas adicionales y referencias
- Zuvarox T, Belletieri C; Malabsorption Syndromes. StatPearls, July 2021.
- Ozaki RKF, Speridiao PDGL, Soares ACF, et al; Intestinal fructose malabsorption is associated with increased lactulose fermentation in the intestinal lumen. J Pediatr (Rio J). 2018 Nov - Dec;94(6):609-615. doi: 10.1016/j.jped.2017.08.006. Epub 2017 Oct 28.
- Montoro-Huguet MA, Belloc B, Dominguez-Cajal M; Small and Large Intestine (I): Malabsorption of Nutrients. Nutrients. 2021 Apr 11;13(4). pii: nu13041254. doi: 10.3390/nu13041254.
- Massironi S, Cavalcoli F, Rausa E, et al; Understanding short bowel syndrome: Current status and future perspectives. Dig Liver Dis. 2020 Mar;52(3):253-261. doi: 10.1016/j.dld.2019.11.013. Epub 2019 Dec 28.
- Brar HS, Aloysius MM, Shah NJ; Tropical Sprue. StatPearls, Jan 2023.
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About the authorView full bio

Dr Colin Tidy, MRCGP
Médico General, Autor Médico
MBBS, MRCGP, MRCP (Paediatrics), DCH
Dr Colin Tidy is an NHS Doctor, based in Oxfordshire.
About the reviewerView full bio

Dr Colin Tidy, MRCGP
Médico General, Autor Médico
MBBS, MRCGP, MRCP (Paediatrics), DCH
Dr Colin Tidy is an NHS Doctor, based in Oxfordshire.
Historial del artículo
La información en esta página está escrita y revisada por pares por clínicos calificados.
Next review due: 2 Nov 2027
30 Nov 2022 | Última versión
1 Aug 2017 | Publicado originalmente
Escrito por:
Dr Colin Tidy, MRCGP

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