Malabsorción gastrointestinal
Revisado por pares por Dr Colin Tidy, MRCGPÚltima actualización por Dr Hayley Willacy, FRCGP Última actualización 30 Nov 2022
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En esta serie:Enfermedad celíacaDermatitis herpetiforme
Gastrointestinal malabsorption syndrome means a failure to fully absorb digested foods from the gut (bowel) into your body. There are many different causes. Prolonged intestinal malabsorption may cause problems because of a lack of carbohydrates, proteins, fats, minerals and vitamins that are essential to keep you healthy.
The treatment will depend on the cause of malabsorption but will also include supplements and other ways to make up for the reduced amount of carbohydrate, protein, fat, minerals and vitamins getting into your gastrointestinal tract.
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Gastrointestinal malabsorption means your gut cannot absorb enough nutrients from food.
Symptoms include tiredness, weight loss, and persistent diarrhoea.
Stools may be pale, bulky, smelly, and difficult to flush.
It can cause deficiencies such as iron, folate, and vitamin B12 deficiency.
Common causes in the UK are coeliac disease, Crohn's disease, and chronic pancreatitis.
Diagnosis involves blood tests, stool tests, and sometimes imaging scans.
Treatment focuses on the underlying cause and nutritional support.
What are the symptoms of gastrointestinal malabsorption?
There may be no symptoms if the malabsorption is mild and has not continued for very long. More severe or persistent malabsorption may lead to:
Cansancio (fatiga)
This is because of a lack of energy as you are not absorbing nutrients and essential vitamins and minerals from food.
Pérdida de peso
If you can't absorb enough energy (calories) from your food then this will cause you to lose weight (and may cause poor growth in children).
Persistent (chronic) diarrhoea
This is a common symptom of persistent malabsorption.
Pale, bulky and smelly stools (steatorrhoea)
This is because there is excessive fat in the stools and they become pale, bulky and very smelly. Fatty stools float and are difficult to flush away. They often leave a greasy rim around the pan.
Intestinal malabsorption may also cause:
Abnormal bleeding, caused by low vitamin K.
Edema, which occurs because of insufficient protein and calories absorbed into the body.
There may also be other symptoms due to the particular underlying condition that is causing the malabsorption.
What are the causes of gastrointestinal malabsorption?
The most common causes in the UK are enfermedad celíaca, enfermedad de Crohn and chronic pancreatitis. However, the malabsorption of simple carbohydrates affects about 1 in 4 people in Europe. Some diseases associated with malabsorption are found more often in some families - for example, coeliac disease, Crohn's disease, fibrosis quística and lactose intolerance.
The causes of gastrointestinal malabsorption include:
Problems with absorbing food from the gut (bowel) into your body
Enfermedad celíaca - a long-term disease that mostly affects the small intestine.
Soya milk intolerance.
Fructose intolerance.
Infection - for example, intestinal tuberculosis, la diarrea del viajero.
Immune deficiency - for example, infección por VIH.
Pancreatic insufficiency - for example, fibrosis quística, pancreatitis crónica, cáncer de páncreas.
Structural causes
Malabsorption may be cause by loss of part of the bowel that is essential to absorb the broken down (digested) food into the body - for example:
Removal of the stomach or part of the bowel after a stomach or bowel operation.
Causes outside the bowel
Ejemplos incluyen:
Eating disorders: anorexia nerviosa, bulimia nerviosa.
¿Qué pruebas se necesitan?
Initial tests will include análisis de sangre y stool tests. Further tests may include an abdominal ultrasonido, barium studies and a tomografía computarizada (TC) o una escaneo de resonancia magnética (IRM). Any further tests will depend on the likely underlying cause of the intestinal malabsorption.
What are the treatments for gastrointestinal malabsorption?
The treatment will mainly depend on the underlying cause of the malabsorption. However, treatment will also be needed to increase the amount of essential nutrients in the body, including carbohydrates, proteins, fats, minerals and fat-soluble vitamins (nutritional support).
Selecciones del paciente para Problemas intestinales

Salud digestiva
enfermedad de Crohn
La enfermedad de Crohn es una afección que causa inflamación de la pared del intestino (tracto gastrointestinal). Cualquier parte del intestino puede verse afectada.
por la Dra. Toni Hazell, MRCGP

Salud digestiva
Úlcera duodenal
Una úlcera duodenal suele ser causada por una infección con un germen (bacteria) llamado Helicobacter pylori (H. pylori). Un tratamiento de 4 a 8 semanas con medicamentos que suprimen el ácido permitirá que la úlcera sane. Además, un tratamiento de una semana con dos antibióticos más un medicamento que suprime el ácido generalmente eliminará la infección por H. pylori. Esto generalmente previene que la úlcera regrese. Los medicamentos antiinflamatorios utilizados para tratar condiciones como la artritis a veces causan úlceras duodenales. Sería muy inusual que a una persona con una úlcera duodenal conocida se le administrara medicación antiinflamatoria, pero si no hay absolutamente ninguna alternativa, entonces se puede administrar con medicación que suprime el ácido a largo plazo.
por la Dra. Toni Hazell, MRCGP
Preguntas frecuentes
Can malabsorption be cured?
The treatment for malabsorption primarily focuses on addressing the underlying condition causing it. Therefore, whether it can be 'cured' depends on the specific cause. Additionally, part of the treatment involves ensuring the body receives essential nutrients like carbohydrates, proteins, fats, minerals, and fat-soluble vitamins through nutritional support.
What happens if fat is not absorbed properly?
If fat is not absorbed properly, it can lead to pale, bulky, and very smelly stools. These stools, known as steatorrhoea, contain excessive fat, often float, are difficult to flush, and can leave a greasy rim around the toilet pan.
Are there any health complications from long-term malabsorption?
Yes, long-term malabsorption can lead to several complications due to insufficient nutrient absorption. These include iron deficiency, iron-deficiency anaemia, folate deficiency, vitamin B12 deficiency, abnormal bleeding due to low vitamin K, and vitamin D deficiency, which can manifest as rickets or osteomalacia. Oedema can also occur because of insufficient protein and calories absorbed into the body.
Can malabsorption be caused by lifestyle factors like eating disorders?
Yes, malabsorption can be influenced by factors outside the bowel, including eating disorders such as anorexia nervosa and bulimia nervosa. An overactive thyroid gland (hyperthyroidism) can also be a cause.
Lecturas adicionales y referencias
- Zuvarox T, Belletieri C; Malabsorption Syndromes. StatPearls, July 2021.
- Ozaki RKF, Speridiao PDGL, Soares ACF, et al; Intestinal fructose malabsorption is associated with increased lactulose fermentation in the intestinal lumen. J Pediatr (Rio J). 2018 Nov - Dec;94(6):609-615. doi: 10.1016/j.jped.2017.08.006. Epub 2017 Oct 28.
- Montoro-Huguet MA, Belloc B, Dominguez-Cajal M; Small and Large Intestine (I): Malabsorption of Nutrients. Nutrients. 2021 Apr 11;13(4). pii: nu13041254. doi: 10.3390/nu13041254.
- Massironi S, Cavalcoli F, Rausa E, et al; Understanding short bowel syndrome: Current status and future perspectives. Dig Liver Dis. 2020 Mar;52(3):253-261. doi: 10.1016/j.dld.2019.11.013. Epub 2019 Dec 28.
- Brar HS, Aloysius MM, Shah NJ; Tropical Sprue. StatPearls, Jan 2023.
Sobre el autorVer biografía completa

Dr Colin Tidy, MRCGP
Médico General, Autor Médico
MBBS, MRCGP, MRCP (Paediatrics), DCH
El Dr. Colin Tidy es un médico del NHS, con sede en Oxfordshire.
Acerca del revisorVer biografía completa

Dr Colin Tidy, MRCGP
Médico General, Autor Médico
MBBS, MRCGP, MRCP (Paediatrics), DCH
El Dr. Colin Tidy es un médico del NHS, con sede en Oxfordshire.
Historial del artículo
La información en esta página está escrita y revisada por pares por clínicos calificados.
Artículo también disponible en Inglés, Alemán, Español, Francés, Italiano, Portugués, Hindi, Hebreo, Árabe, y Sueco.
Next review due: 2 Nov 2027
30 Nov 2022 | Última versión
1 Aug 2017 | Publicado originalmente
Escrito por:
Dr Colin Tidy, MRCGP

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