Can I take Oxypro and Quinine together?
Drug interaction guide
Originally published 25 Jan 2026
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Taking these two medicines together can increase the risk of a serious heart rhythm problem. It may also lead to higher levels of oxycodone in your blood, which can increase the risk of dangerous side effects like extreme sleepiness or breathing difficulties.
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Why this happens
Quinine can interfere with the way your liver breaks down oxycodone (the active ingredient in Oxypro), leading to a buildup of the painkiller in your system. Additionally, both drugs have the potential to affect the electrical activity of your heart (prolonging the QT interval), and using them together increases this risk.
What you should do
You should speak to your doctor before taking these medicines together. Your doctor may need to adjust your doses or monitor your heart health more closely. Seek immediate medical help if you feel dizzy, faint, or experience a fast or pounding heartbeat.
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Using other medicines
Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Descargo de responsabilidad
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Historia del artículo
La información de esta página ha sido redactada y revisada por médicos cualificados.
25 Enero 2026 | Publicado originalmente
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