Can I take Oxycodone and Pregabalin together?

Por qué sucede esto

Both medicines act as central nervous system (CNS) depressants. This means they both slow down brain activity and the signals that tell your body to breathe. When taken together, their effects add up (an additive effect), making the impact on your brain and lungs much stronger than if you took either medicine alone.

You must only take these two medicines together if they have been specifically prescribed by the same doctor who is aware you are taking both. Your doctor should start you on the lowest possible doses and monitor you closely.

Seek emergency medical help immediately if you or someone taking these medicines experiences:

• Very slow or shallow breathing

• Extreme sleepiness or inability to stay awake

• Limp muscles or cold, clammy skin

• Pinpoint pupils

• A slow heartbeat or fainting

Mental health disorders

Pregabalin can cause suicidal thoughts or an urge to self-harm. You must seek medical help immediately if your mood changes or you have thoughts of hurting yourself.

Embarazo

El uso de pregabalina durante los primeros tres meses de embarazo puede aumentar el riesgo de defectos de nacimiento. Se debe utilizar anticoncepción efectiva durante el tratamiento.

Opioid dependence/Addiction

Oxycodone is highly addictive. Long-term use can lead to physical dependence and withdrawal symptoms if stopped suddenly.

Dependencia de drogas y abstinencia

Pregabalin carries a risk of dependence and addiction. Do not stop taking it suddenly, as this can cause severe withdrawal symptoms such as seizures or anxiety.

Depresión respiratoria

Oxycodone can dangerously slow or stop your breathing, especially when first starting or if the dose is increased. This risk is much higher if taken with alcohol or other sedatives.

Alcohol

It is best to avoid or strictly limit alcohol while taking these medicines. Both oxycodone and pregabalin cause drowsiness and dizziness; alcohol significantly increases these effects. Combining alcohol with these medicines can lead to dangerous breathing problems, extreme sleepiness, and loss of consciousness.

Jugo de toronja

Avoid drinking grapefruit juice or eating grapefruit while taking oxycodone. Grapefruit can increase the amount of oxycodone in your blood, which makes side effects like extreme sleepiness and slowed breathing more likely.

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Descargo de responsabilidad

Esta información es solo para fines educativos generales y no debe considerarse como un sustituto del consejo médico profesional. Siempre consulte a su médico de cabecera, farmacéutico u otro profesional de la salud calificado antes de tomar decisiones sobre sus medicamentos. Las circunstancias individuales pueden variar, y solo un profesional de la salud que conozca su historial médico puede proporcionar orientación personalizada.