Can I take Oestrogel pump-pack /actuation and Solifenacin together?
Drug interaction guide
Originally published 25 Jan 2026
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There is no known direct interaction between Oestrogel (estradiol) and solifenacin. They work in different ways and are processed by different pathways in the body.
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Why this happens
Oestrogel is a hormone replacement therapy (HRT) absorbed through the skin, while solifenacin is an antimuscarinic medicine used for overactive bladder. They do not compete for the same metabolic enzymes or interfere with each other's effects.
What you should do
You can safely use these two medications together. Always follow the dosage instructions provided by your doctor for both treatments. If you notice any new or unusual symptoms, or if your bladder symptoms do not improve, consult your healthcare professional.
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Using other medicines
Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Descargo de responsabilidad
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Historia del artículo
La información de esta página ha sido redactada y revisada por médicos cualificados.
25 Enero 2026 | Publicado originalmente
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